aschantin

from flower buds of Magnolia fargesii; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 10/01/2015 - "Notably, aschantin treatment decreased c-Jun stability through inhibition of the mTORC2-Akt signaling pathway, which suppressed EGF-induced anchorage-independent cell transformation in non-malignant JB6 Cl41 and HaCaT cells and colony growth of LNCaP and MIAPaCa-2 cancer cells in soft agar. " 01/01/2021 - "Several compounds in fraction B, such as rengyolone, licochalcone A, sugiol, and spinasterol, might have been known to have activity against cancer cells, as well as aschantin and lirioresinol B dimethyl ether from fraction E. "
2.	Neoplastic Cell Transformation 10/01/2015 - "Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation."

1.	TOR Serine-Threonine Kinases
2.	Phosphotransferases (Kinase)
3.	Epidermal Growth Factor (EGF)
4.	Agar
5.	Rengyolone
6.	sugiol
7.	licochalcone A
8.	spinasterol
9.	lirioresinol B dimethyl ether