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sanguilutine

has phytogenic antineplastic activity; structure in first source

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Benzophenanthridines
    - sanguilutine: 5
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Phenanthridines: 3
      - Benzophenanthridines
        sanguilutine: 5
  - 4 or More Rings Heterocyclic Compounds
    - Benzophenanthridines
      - sanguilutine: 5

Experts

1.	Hammerová, Jindřiška: 2 articles (07/2012 - 04/2011)
2.	Slaninová, Iva: 2 articles (07/2012 - 04/2011)
3.	Táborská, Eva: 2 articles (07/2012 - 04/2011)
4.	Uldrijan, Stjepan: 2 articles (07/2012 - 04/2011)
5.	Slaninová, I: 2 articles (04/2010 - 01/2001)
6.	Táborská, E: 2 articles (04/2010 - 01/2001)
7.	Vaculová, Alena Hyršlová: 1 article (07/2012)
8.	Gelnarová, E: 1 article (04/2010)
9.	Hammerová, J: 1 article (04/2010)
10.	Slunská, Z: 1 article (04/2010)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 07/01/2012 - "Necroptosis modulated by autophagy is a predominant form of melanoma cell death induced by sanguilutine." 07/01/2012 - "We show that the plant quaternary benzo[c]phenanthridine alkaloid sanguilutine (SL) is a strong inducer of caspase-independent non-apoptotic death in human melanoma cells. " 04/01/2011 - "The effects of five BAs (sanguinarine, chelerythrine, chelidonine, sanguilutine, and chelilutine) on human malignant melanoma cell lines were compared. " 10/20/2023 - "In the present study we studied the effect of six quaternary benzophenanthridine alkaloids (QBAs), sanguinarine, chelerythrine, sanguirubine, chelirubine, sanguilutine, and chelilutine, on Jurkat leukemia cells, WT, and cell death deficient lines derived from them, CASP3/7/6-/- and FADD-/-, and on solid tumor, human malignant melanoma, A375 cells. "
2.	Neoplasms (Cancer) 04/01/2010 - "Effect of quaternary benzo[c]phenanthridine alkaloids sanguilutine and chelilutine on normal and cancer cells." 10/20/2023 - "In the present study we studied the effect of six quaternary benzophenanthridine alkaloids (QBAs), sanguinarine, chelerythrine, sanguirubine, chelirubine, sanguilutine, and chelilutine, on Jurkat leukemia cells, WT, and cell death deficient lines derived from them, CASP3/7/6-/- and FADD-/-, and on solid tumor, human malignant melanoma, A375 cells. "
3.	Leukemia 10/20/2023 - "In the present study we studied the effect of six quaternary benzophenanthridine alkaloids (QBAs), sanguinarine, chelerythrine, sanguirubine, chelirubine, sanguilutine, and chelilutine, on Jurkat leukemia cells, WT, and cell death deficient lines derived from them, CASP3/7/6-/- and FADD-/-, and on solid tumor, human malignant melanoma, A375 cells. "
4.	Carcinoma (Carcinomatosis) 01/01/2001 - "We compared the effects of four quaternary benzo[c]phenanthridine alkaloids--chelerythrine, chelilutine, sanguinarine, and sanguilutine--and two quaternary protoberberine alkaloids-berberine and coptisine--on the human cell line HeLa (cervix carcinoma cells) and the yeasts Saccharomyces cerevisiae and Schizosaccharomyces japonicus var. versatilis. "

Related Drugs and Biologics

1.	Alkaloids
2.	chelilutine
3.	chelerythrine
4.	sanguinarine
5.	Caspase 3 (Caspase-3)
6.	chelirubine
7.	benzo(c)phenanthridine
8.	Caspases
9.	Berberine Alkaloids
10.	chelidonine