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allantopyrone A

from an endophytic fungus, Allantophomopsis; structure in first source

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Pyrones: 35
      - allantopyrone A: 3

Experts

1.	Kataoka, Takao: 2 articles (08/2017 - 02/2015)
2.	Shiono, Yoshihito: 2 articles (08/2017 - 02/2015)
3.	Yokoigawa, Junpei: 2 articles (08/2017 - 02/2015)
4.	Hirano, Seiya: 1 article (08/2017)
5.	Kimura, Ken-Ichi: 1 article (08/2017)
6.	Niwa, Masamitsu: 1 article (08/2017)
7.	Quach, Hue Tu: 1 article (08/2017)
8.	Tanigaki, Riho: 1 article (08/2017)
9.	Yamada, Yuriko: 1 article (08/2017)
10.	Kimura, Ken-ichi: 1 article (02/2015)

Related Diseases

1.	Fibrosarcoma 01/01/2023 - "In the present study, we showed that allantopyrone A up-regulated the protein expression of hypoxia-inducible factor (HIF)-1α in human fibrosarcoma HT-1080 cells. " 01/01/2023 - "Therefore, the present results showed that allantopyrone A interfered with the degradation of HIF-1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells." 01/01/2023 - "Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells."
2.	Hypoxia (Hypoxemia) 01/01/2023 - "In the present study, we showed that allantopyrone A up-regulated the protein expression of hypoxia-inducible factor (HIF)-1α in human fibrosarcoma HT-1080 cells. " 01/01/2023 - "Allantopyrone A interferes with the degradation of hypoxia-inducible factor 1α protein by reducing proteasome activity in human fibrosarcoma HT-1080 cells."
3.	Carcinoma (Carcinomatosis) 08/01/2017 - "We recently reported that allantopyrone A inhibited the nuclear factor-κB (NF-κB) signaling pathway induced by tumor necrosis factor (TNF)-α in human lung carcinoma A549 cells. " 02/01/2015 - "Allantopyrone A, a recently identified α-pyrone metabolite from an endophytic fungus, was found to inhibit the TNF-α-induced expression of ICAM-1 in human lung carcinoma A549 cells. "
4.	Neoplasms (Cancer) 01/01/2023 - "We previously demonstrated that allantopyrone A exhibits anti-cancer, anti-inflammatory, and neuroprotective activities. "

Related Drugs and Biologics

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4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)