origanoside

inhibits melanogenesis; isolated from Origanum vulgare; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Microphthalmos 12/01/2022 - "The in vitro/in vivo melanin inhibitory effects of these plant extracts/phytochemicals are achieved via three main mechanisms: (1) the ethyl acetate extract of Oryza sativa Indica cv., and phytochemicals such as galangin and origanoside could manage melanin biosynthesis through competitive inhibition, non-competitive inhibition or mixed-type inhibition of tyrosinase; (2) phytochemicals such as ginsenoside F1, ginsenoside Rb1 and 4‑hydroxy-3-methoxycinnamaldehyde could inhibit melanogenesis through down-regulating microphthalmia-related transcription factor (MITF) gene expression via different signalling pathways; (3) the ethanolic extracts of Dimorphandra gardneriana, Dimorphandra gardneriana, Lippia microphylla and Schinus terebinthifolius have a good ultraviolet absorption ability and high sun protective factor (SPF) values, thereby inhibiting UV induced melanogenesis in the skin. "
2.	Experimental Melanoma 03/01/2010 - "Skin-whitening capacity in skin fibroblast Hs68 and melanoma B16 cells and in vivo animal test for origanoside (1) were investigated. "
3.	Erythema 03/01/2010 - "Smearing origanoside (1)-gel samples on 12 mice for 10 days increased L, reduced a and erythema-melanin (E/M), and b* was almost unchanged compared with those of samples and untreated groups, indicating that the skin lightened. "

1.	Melanins (Melanin)
2.	Phytochemicals
3.	Monophenol Monooxygenase (Tyrosinase)
4.	Transcription Factors (Transcription Factor)
5.	Plant Extracts
6.	ginsenoside Rb1
7.	ginsenoside F1
8.	galangin
9.	ethyl acetate