HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

mycolylarabinogalactan

a component Mycobacterium tuberculosis cell wall; structure in first source

Also Known As:

mAG cpd

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Galactans: 56
    - mycolylarabinogalactan: 3

Experts

1.	Chêne, Loïc: 1 article (10/2020)
2.	Fabre, Emeline: 1 article (10/2020)
3.	Guérardel, Yann: 1 article (10/2020)
4.	Halloum, Iman: 1 article (10/2020)
5.	Joe, Maju: 1 article (10/2020)
6.	Kremer, Laurent: 1 article (10/2020)
7.	Lowary, Todd L: 1 article (10/2020)
8.	Mariller, Christophe: 1 article (10/2020)
9.	Méry, Alexandre: 1 article (10/2020)
10.	Shen, Lin: 1 article (10/2020)

Related Diseases

1.	Infections 10/01/2020 - "Despite impressive progress made over the past 20 years in our understanding of mycolylarabinogalactan-peptidoglycan (mAGP) biogenesis, the mechanisms by which the tubercle bacillus Mycobacterium tuberculosis adapts its cell wall structure and composition to various environmental conditions, especially during infection, remain poorly understood. " 10/25/1990 - "Thus, it is reasoned that the massive mycolylarabinogalactan of mycobacteria, responsible for aspects of disease pathogenesis and much of the antibody response in infections, is attached to the peptidoglycan framework by the actinomycete-specific diglycosylphosphoryl bridge, L-Rhap-(1----3)-D-GlcNAc-(1----P, perhaps thereby providing a unique target for site-directed chemotherapy of mycobacterial infections."
2.	Tuberculosis (Tuberculoses) 05/15/2004 - "tuberculosis, the 19-kDa lipoprotein and cell wall peptidoglycan (contained in the mycolylarabinogalactan peptidoglycan (mAGP) complex), inhibit macrophage responses to IFN-gamma at a transcriptional level. "

Related Drugs and Biologics

1.	Peptidoglycan (Murein)
2.	Lipoproteins (Lipoprotein)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)