JCM-16021

Analgesic; composed of Radix Paeoniae Lactiflorae, Cortex Magnoliae Officinalis, Rhizoma Corydalis Yanhusuo, Fructus Terminaliae Chebulae, Herba Polygoni Chinensis; Fructus Terminaliae Chebulae and Rhizoma Atractylodis

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bian, Zhao-Xiang: 2 articles (01/2012 - 02/2010)
2.	Sung, Joseph J Y: 2 articles (01/2012 - 02/2010)
3.	Xu, Hong-Xi: 2 articles (01/2012 - 02/2010)
4.	Bian, Zhao Xiang: 1 article (11/2021)
5.	Cao, Pei Hua: 1 article (11/2021)
6.	Chan, Kam Leung: 1 article (11/2021)
7.	Cheng, Chung Wah: 1 article (11/2021)
8.	Cheong, Pui Kuan: 1 article (11/2021)
9.	Ching, Jessica: 1 article (11/2021)
10.	Koh, Matthew: 1 article (11/2021)

Related Diseases

1.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 11/13/2021 - "Efficacy and safety of Chinese medicine JCM-16021 for diarrhea-predominant irritable bowel syndrome: study protocol for a multi-center, randomized, double-blind, placebo controlled clinical trial." 01/01/2012 - "The present study aimed to investigate the analgesic effect of JCM-16021, a revised traditional Chinese herbal formula, on postinflammatory irritable bowel syndrome (PI-IBS) in rats. " 01/01/2012 - "JCM-16021, a Chinese Herbal Formula, Attenuated Visceral Hyperalgesia in TNBS-Induced Postinflammatory Irritable Bowel Syndrome through Reducing Colonic EC Cell Hyperplasia and Serotonin Availability in Rats."
2.	Diarrhea 11/13/2021 - "Efficacy and safety of Chinese medicine JCM-16021 for diarrhea-predominant irritable bowel syndrome: study protocol for a multi-center, randomized, double-blind, placebo controlled clinical trial."
3.	Visceral Pain 02/21/2010 - "Analgesic effects of JCM-16021 on neonatal maternal separation-induced visceral pain in rats."
4.	Abdominal Pain (Pain, Abdominal) 11/13/2021 - "The protocol will provided a detailed procedure to conduct a clinical trial and verify if the Chinese medicine JCM-16021 would significantly improve the overall symptoms of IBS-D with LSSD pattern of TCM by relieving abdominal pain, reducing stool frequency, improving the stool consistency and improving quality of life. "
5.	Hypersensitivity (Allergy) 02/21/2010 - "JCM-16021 can attenuate visceral hypersensitivity, and this analgesic effect may be mediated through the serotonin signaling pathway in the colon of rats."

Related Drugs and Biologics

1.	Analgesics (Analgesic Drugs)
2.	Serotonin (5 Hydroxytryptamine)