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2- (3- benzyl- 4- oxo- 3,4,5,6,7,8- hexahydrobenzo(4,5)thieno(2,3- d)pyrimidin- 2- ylsulfanylmethyl)- oxazole- 4- carboxylic acid (2-pyrrolidin-1-yl-ethyl)amide

induces autophagic cell death; structure in first source

Also Known As:

autophagonizer

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - 2-(3-benzyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo(4,5)thieno(2,3-d)pyrimidin-2-ylsulfanylmethyl)-oxazole-4-carboxylic acid (2-pyrrolidin-1-yl-ethyl)amide: 1
  - Thiophenes: 257
    - 2-(3-benzyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo(4,5)thieno(2,3-d)pyrimidin-2-ylsulfanylmethyl)-oxazole-4-carboxylic acid (2-pyrrolidin-1-yl-ethyl)amide: 1
Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiophenes: 257
    - 2-(3-benzyl-4-oxo-3,4,5,6,7,8-hexahydrobenzo(4,5)thieno(2,3-d)pyrimidin-2-ylsulfanylmethyl)-oxazole-4-carboxylic acid (2-pyrrolidin-1-yl-ethyl)amide: 1

Experts

1.	Chen, Luxi: 1 article (10/2016)
2.	Kumar, Dhiraj: 1 article (10/2016)
3.	Lee, Jiyong: 1 article (10/2016)
4.	Nguyen, Jennifer: 1 article (10/2016)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2016 - "These findings highlight that intrinsic apoptosis is not also involved in the induction of cellular death by the autophagonizer suggesting the autophagonizer is a promising candidate for anticancer therapeutics for cancer cells that are resistant to apoptosis-inducing chemotherapy."

Related Therapies and Procedures

1.	Therapeutics
2.	Drug Therapy (Chemotherapy)