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2- (2- N,N- dimethylaminoethylamine- 1- carbonyl)- 1H- quinolin- 4- one hydrochloride

structure in first source

Also Known As:

KYNA-HCl

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Hydroxyquinolines: 9
        Kynurenic Acid: 693
        2-(2-N,N-dimethylaminoethylamine-1-carbonyl)-1H-quinolin-4-one hydrochloride: 2
- Heterocyclic Acids
  - Xanthurenates
    - Kynurenic Acid: 693
      - 2-(2-N,N-dimethylaminoethylamine-1-carbonyl)-1H-quinolin-4-one hydrochloride: 2

Experts

1.	Fülöp, Ferenc: 2 articles (05/2011 - 09/2009)
2.	Vécsei, László: 2 articles (05/2011 - 09/2009)
3.	Mándi, Yvette: 1 article (05/2011)
4.	Németh, Balázs: 1 article (05/2011)
5.	Ocsovszky, Imre: 1 article (05/2011)
6.	Tiszlavicz, Zoltán: 1 article (05/2011)
7.	Tápai, Katalin: 1 article (05/2011)
8.	Bohár, Zsuzsanna: 1 article (09/2009)
9.	Párdutz, Arpád: 1 article (09/2009)
10.	Tajti, János: 1 article (09/2009)

Related Diseases

1.	Necrosis 05/01/2011 - "The aim of this study was to compare the effects of KynA with those of a new analogue, 2-(2-N,N-dimethylaminoethylamine-1-carbonyl)-1H-quinolin-4-one hydrochloride on tumour necrosis factor-α (TNF-α) production and high mobility group box protein 1 (HMGB1) secretion. "
2.	Pain (Aches) 09/01/2009 - "Since NMDA receptors play a crucial role in trigeminal pain processing, the aim of our experiments was to compare the effects of L-kynurenine (L-KYN) combined with probenecid (PROB) or with 2-(2-N,N-dimethylaminoethylamine-1-carbonyl)-1H-quinolin-4-one hydrochloride alone, a newly synthetized KYNA derivative, on the NTG-induced nNOS expression in the rat TNC. "

Related Drugs and Biologics

1.	HMGB1 Protein (HMG1)
2.	Proteins (Proteins, Gene)
3.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
4.	Probenecid (Benemid)
5.	Kynurenine