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(E)- 1- (3,4- dihydroxyphenethyl)- 3- styrylurea

a synthetic compound that induces apoptotic cell death in melanoma cells; structure in first source

Also Known As:

PAPU1 cpd

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - (E)-1-(3,4-dihydroxyphenethyl)-3-styrylurea: 2

Experts

1.	Jang, Yong-Suk: 1 article (10/2010)
2.	Kim, Beom-Tae: 1 article (10/2010)
3.	Kim, Ji-Hae: 1 article (10/2010)
4.	Kim, Tae-Geum: 1 article (10/2010)
5.	Lee, Jeong-Chae: 1 article (10/2010)
6.	Yu, Ji-Yeon: 1 article (10/2010)
7.	Hwang, Ki Jun: 1 article (12/2009)
8.	Jang, Young Oh: 1 article (12/2009)
9.	Kim, Beom Tae: 1 article (12/2009)
10.	Kim, Ji Hae: 1 article (12/2009)

Related Diseases

1.	Neoplasms (Cancer) 12/31/2009 - "In this study, we examined the anti-tumor activity and cellular mechanism of the synthetic compound (E)-1-(3,4-dihydroxyphenethyl)-3-styrylurea (PAPU1) using melanoma B16/F10 and M-3 cells. "
2.	Experimental Melanoma 12/31/2009 - "In this study, we examined the anti-tumor activity and cellular mechanism of the synthetic compound (E)-1-(3,4-dihydroxyphenethyl)-3-styrylurea (PAPU1) using melanoma B16/F10 and M-3 cells. "
3.	Melanoma (Melanoma, Malignant) 12/31/2009 - "Induction of caspase-dependent apoptosis in melanoma cells by the synthetic compound (E)-1-(3,4-dihydroxyphenethyl)-3-styrylurea." 10/01/2010 - "We have previously shown the capacity of one PAPU compound, (E)-1-(3,4-dihydroxyphenethyl)-3-styrylurea (PAPU1), to induce caspase-dependent apoptosis in melanoma cells. "

Related Drugs and Biologics

1.	adenylyl-(3'-5')-uridine 5'-phosphate (pApU)