momordin

07/15/2022 - "This study evaluated the apoptosis-inducing ability of momordin Ic against cholangiocarcinoma (CCA) cells and the respective underlying mechanisms. "
07/15/2022 - "Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells."

06/15/2023 - "In this study, momordin Ic (MIC), a triterpenoid saponin derived from Kochia scoparia (L.) Schrad., specifically enhance the antiproliferative effect of recombinant MAP30 (a type I ribosome inactivating protein, RIP) in breast cancer cells. "

04/01/2019 - "Thus momordin Ic may be a promising candidate with anti-cancer bioactivity."
04/01/2019 - "To further elucidate the anti-cancer activity of Momordin Ic, we analyzed the suppressive effects of Momordin Ic on cell migration and invasion. "
06/01/2013 - "The aim of this work was to elucidate the anti-tumor effect of momordin Ic and the signal transduction pathways involved. "
06/01/2013 - "So far, there is little scientific evidence for momordin Ic with regard to the anti-tumor activities. "
01/01/2016 - "Those results suggest that momordin Ic has great potential as a nutritional preventive strategy in cancer therapy. "

04/01/2019 - "Momordin Ic was previously found to induce liver cancer cell apoptosis and autophagy. "
06/01/2020 - "We previously reported that Momordin Ic, a natural triterpenoid saponin from the fruit of Kochia scoparia (L.) Schrad., exerts good anti-invasive activity on liver cancer partly by altering E-cadherin, VCAM-1, ICAM-1 and MMP-9. "

01/01/2020 - "Momordin Ic (MC), a new type of SENP1 inhibitor, reduces LPS-induced cellular inflammation by depressing SENP1 expression. "
01/01/2021 - "Fructus Kochiae (or Kochia scoparia) and its principle saponin, Momordin Ic, have been reported to protect against inflammation. "