HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

4- chloro- N- (2- ((5- trifluoromethyl- 2- pyridyl)sulfonyl)ethyl)benzamide

structure in first source

Also Known As:

GSK 3787; GSK-3787; GSK3787

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Hutter, Victoria: 1 article (03/2021)
2.	Lione, Lisa A: 1 article (03/2021)
3.	Mackenzie, Louise S: 1 article (03/2021)
4.	Perez Diaz, Noelia: 1 article (03/2021)
5.	Broaddus, Russell R: 1 article (01/2019)
6.	Chen, Weidong: 1 article (01/2019)
7.	Chrieki, Sarah P: 1 article (01/2019)
8.	Deguchi, Yasunori: 1 article (01/2019)
9.	Gagea, Mihai: 1 article (01/2019)
10.	Gao, Shen: 1 article (01/2019)

Related Diseases

1.	Carcinogenesis 11/01/2023 - "GSK3787 significantly suppressed GAC carcinogenesis in PpardTG mice. " 01/01/2019 - "Treatment with PPARD agonist GW501516 enhanced colorectal cancer tumorigenesis in ApcΔ580 mice, whereas treatment with PPARD antagonist GSK3787 suppressed tumorigenesis. "
2.	Inflammation (Inflammations) 11/01/2016 - "The PPARδ-selective antagonist GSK3787 ameliorated the observed inflammation in the skin of the experimental mice. " 03/19/2021 - "We studied the PPARβ/δ-regulation of lipopolysaccharide (LPS) induced inflammation (indicated by release of nitrite and IL-6) of rat pulmonary artery, using different combinations of agonists (GW0742 or L-165402) and antagonists (GSK3787 or GSK0660). "
3.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2019 - "Treatment with PPARD agonist GW501516 enhanced colorectal cancer tumorigenesis in ApcΔ580 mice, whereas treatment with PPARD antagonist GSK3787 suppressed tumorigenesis. "
4.	Neuroblastoma 11/30/2023 - "Because MEHP can bind to the PPARβ/δ protein and initiate the expression of the downstream gene angiopoietin-like 4 (ANGPTL4), the PPARβ/δ-specific agonist GW501516 and antagonist GSK3787, the recombinant human ANGPTL4 protein, and the knockdown of gene expression confirmed the regulation of the PPARβ/δ-ANGPTL4 axis on the malignant phenotype of neuroblastoma. "
5.	Neoplasms (Cancer) 09/01/2010 - "Cell proliferation was unchanged in response to either GW0742 or GSK3787 in human cancer cell lines. " 09/01/2010 - "GSK3787 antagonized GW0742-induced expression of Angptl4 in mouse fibroblasts, mouse keratinocytes, and human cancer cell lines. "

Related Drugs and Biologics

1.	(4- (((2- (3- fluoro- 4- (trifluoromethyl)phenyl)- 4- methyl- 1,3- thiazol- 5- yl)methyl)sulfanyl)- 2- methylphenoxy)acetic acid
2.	GW 501516
3.	Angiopoietins
4.	Proteins (Proteins, Gene)
5.	Nitrites
6.	Lipopolysaccharides
7.	GSK0660
8.	human ANGPTL4 protein
9.	mono-(2-ethylhexyl)phthalate