HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

NIR-conPK

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - NIR-conPK: 1

Experts

1.	Bai, Mingfeng: 1 article (12/2009)
2.	Bornhop, Darryl: 1 article (12/2009)
3.	Cudaback, Eiron: 1 article (12/2009)
4.	Kreitzer, Faith R: 1 article (12/2009)
5.	Lin, Yi Hsing: 1 article (12/2009)
6.	Manning, H Charles: 1 article (12/2009)
7.	Möller, Thomas: 1 article (12/2009)
8.	Sexton, Michelle: 1 article (12/2009)
9.	Stella, Nephi: 1 article (12/2009)
10.	Woodruff, Grace: 1 article (12/2009)

Related Diseases

1.

Astrocytoma (Pilocytic Astrocytoma)

12/18/2009 - " these results suggest that NIR-conPK binds to a protein that is related to TSPO, and expressed by astrocytomas and microglia. "
12/18/2009 - "Accordingly, treating intact astrocytoma cells and microglia in culture with cytokines led to significant changes in the amount of NIR-conPK specific binding without corresponding change in TSPO expression. "
12/18/2009 - "Conversely, we found that NIR-conPK did not compete for [(3)H]-PK 11195 binding in astrocytoma cell homogenate, but exhibited specific binding in intact astrocytoma cells in culture with nanomolar affinity, suggesting that NIR-conPK binds to a protein distinct, but related to, TSPO. "
12/18/2009 - "Binding of NIR-conPK and NIR-6T to astrocytomas and microglial cells: evidence for a protein related to TSPO."

Related Drugs and Biologics

1.	Cytokines
2.	Proteins (Proteins, Gene)
3.	NIR-6T
4.	PK 11195 (PK11195)