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N-methyl-delta-3,3-dihydroindole-2,2 diketone

a cytokine regulator that belongs to dihydroindole family

Also Known As:

Natura-alpha

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - N-methyl-delta-3,3-dihydroindole-2,2 diketone: 2

Experts

1.	Mencher, Simon K: 2 articles (07/2011 - 02/2010)
2.	Wang, Long G: 2 articles (07/2011 - 02/2010)
3.	Daniels, Garrett: 1 article (07/2011)
4.	Ferrari, Anna: 1 article (07/2011)
5.	Lee, Peng: 1 article (07/2011)
6.	Lepor, Hebert: 1 article (07/2011)
7.	Li, Yirong: 1 article (07/2011)
8.	Ligr, Martin: 1 article (07/2011)
9.	Liu, Xiaomei: 1 article (07/2011)
10.	McCarron, James P: 1 article (07/2011)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 07/01/2011 - "Natura-alpha targets forkhead box m1 and inhibits androgen-dependent and -independent prostate cancer growth and invasion."
2.	Neoplasms (Cancer) 07/01/2011 - "The antitumor effects of Natura-alpha were examined in nude mice tumor xenograft models, and in a patient with advanced hormone-refractory metastatic PC. " 07/01/2011 - "However, the anticancer properties of Natura-alpha, an indirubin derivative, are not well studied in solid tumors, particularly in PC. "
3.	Rheumatoid Arthritis 02/01/2010 - "Since Natura-alpha inhibits a large spectrum of important pathogenic factors in CIA, it may provide a new and powerful approach to the treatment of rheumatoid arthritis and other inflammatory diseases."
4.	Experimental Arthritis 02/01/2010 - "Treatment of collagen-induced arthritis by Natura-alpha via regulation of Th-1/Th-17 responses."
5.	Arthritis (Polyarthritis) 02/01/2010 - "Natura-alpha treatment was administered before or during arthritis induction. "

Related Drugs and Biologics

1.	Hormones (Hormone)
2.	Androgens
3.	indirubin