dendropanoxide

antimalarial isolated from Denddropanax morbifera; structure in first source

Networked: 4 relevant articles (2 outcomes, 1 trials/studies)

1.	Fibrosis (Cirrhosis) 12/27/2021 - "In this study, we showed that dendropanoxide (DPX), isolated from Dendropanax morbifera, had anti-fibrotic effects on hepatic fibrosis by inhibiting hepatic stellate cell (HSC) activation. " 12/27/2021 - "Dendropanoxide, a Triterpenoid from Dendropanax morbifera, Ameliorates Hepatic Fibrosis by Inhibiting Activation of Hepatic Stellate Cells through Autophagy Inhibition." 01/01/2023 - "Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/C Mice."
2.	Acute Kidney Injury (Acute Renal Failure) 11/01/2020 - "Protective effects of dendropanoxide isolated from Dendropanax morbifera against cisplatin-induced acute kidney injury via the AMPK/mTOR signaling pathway."
3.	Osteosarcoma (Osteogenic Sarcoma) 01/01/2013 - "Dendropanoxide induces autophagy through ERK1/2 activation in MG-63 human osteosarcoma cells and autophagy inhibition enhances dendropanoxide-induced apoptosis."
4.	Inflammation (Inflammations) 01/01/2023 - "Dendropanoxide Alleviates Thioacetamide-induced Hepatic Fibrosis via Inhibition of ROS Production and Inflammation in BALB/C Mice."

1.	Triterpenes
2.	Cisplatin (Platino)
3.	Thioacetamide (Thioacetamid)