HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanol

a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity; structure in first source
Also Known As:
AZD8055
Networked: 90 relevant articles (7 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Guichard, Sylvie M: 6 articles (01/2019 - 04/2012)
2. Guichard, Sylvie: 4 articles (02/2013 - 01/2010)
3. Houghton, Peter J: 3 articles (06/2017 - 02/2012)
4. Latorre, Alfonso: 2 articles (01/2021 - 07/2014)
5. Somoza, Álvaro: 2 articles (01/2021 - 07/2014)
6. Wessels, Lodewyk F A: 2 articles (01/2020 - 11/2016)
7. Fan, Rong: 2 articles (05/2019 - 01/2016)
8. Hu, Shurong: 2 articles (05/2019 - 01/2016)
9. Wang, Lei: 2 articles (05/2019 - 01/2016)
10. Wang, Zhengting: 2 articles (05/2019 - 01/2016)

Related Diseases

1. Neoplasms (Cancer)
2. Breast Neoplasms (Breast Cancer)
3. Renal Cell Carcinoma (Grawitz Tumor)
4. Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
5. Chordoma

Related Drugs and Biologics

1. Mechanistic Target of Rapamycin Complex 1
2. Sirolimus (Rapamycin)
3. Tamoxifen
4. Apoptosis Regulatory Proteins
5. Afatinib
6. DT2216
7. MTOR Inhibitors
8. sapanisertib
9. Adenosine Triphosphate (ATP)
10. Erlotinib Hydrochloride (CP 358,774)

Related Therapies and Procedures

1. Therapeutics
2. Nanospheres
3. Radiotherapy
4. Drug Therapy (Chemotherapy)
5. Oral Administration