jiadifenolide

from Illicium jiadifengpi; structure in first source

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

1.	Neurodegenerative Diseases (Neurodegenerative Disease) 07/07/2014 - "As a potent neurotrophic agent, the sesquiterpenoid jiadifenolide represents a valuable small-molecule lead for the potential therapeutic treatment of neurodegenerative diseases. " 01/01/2018 - "Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies."
2.	Neoplasms (Cancer) 11/06/2015 - "The synthetic jiadifenolide exhibited weak cytotoxicity against five human cancer cell lines. "
3.	Dementia (Dementias) 01/01/2018 - "Like jiadifenolide, memantine (Namenda), one of the few drugs used in the symptomatic treatment of dementias, occupies a unique site on the NMDA receptor complex that creates low binding affinity that is associated with its reduced side-effect profile. "

1.	Sesquiterpenes
2.	Convulsants
3.	N-Methyl-D-Aspartate Receptors (NMDA Receptors)
4.	Memantine (Namenda)