acetylcholinesterase inhibitor from Warszewiczia coccinea (Rubiaceae)
Also Known As:
3beta,6beta-dihydroxy-olean-12-en-28-oic acid; sumaresinolic acid
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Bio-Agent Context: Research Results
|1. ||Alzheimer Disease (Alzheimer's Disease)
- "In addition, nepetidin (2), nepeticin (3), lupendiol (4), (1beta,11alpha)-dihydroxy-lup-20(29)-en-3-one (5), ursolic acid (6), sumaresinolic acid (7) and hederagenin (8), were identified in this Salvia sp. To the best of our knowledge, the compounds 2 and 7 are new constituents in Salvia spp. The acetone, ethanol, butanol and water extracts of the plant were screened for the in vitro inhibitory activity of acetylcholinesterase (AChE) and butyrilcholinesterase (BChE), enzymes which play a role in the Alzheimer disease.
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