KU135

12/22/2011 - "We suggest that KU135 may be a potential candidate for cancer therapy against melanoma."

12/22/2011 - "These finding show that KU135 reduced cell survival, proliferation, and induces apoptosis in melanoma cells. "
12/22/2011 - "The results indicate that KU135 reduced cell viability and cell proliferation in melanoma cells and IC(50) values for A735(DRO), M14(NPA), B16F10 and SKMEL28 cells were 0.82, 0.92, 1.33 and 1.30μM respectively. "
12/22/2011 - "A novel C-terminal HSP90 inhibitor KU135 induces apoptosis and cell cycle arrest in melanoma cells."
12/22/2011 - "KU135 induced a more potent anti-proliferative effect in most melanoma cells versus N-terminal Hsp90 inhibitor 17AAG. "
12/22/2011 - "We investigated a novobiocin-derived Hsp90 C-terminal inhibitor, KU135, for anti-proliferative effects in melanoma cells. "