gambogic amide

a TrkA agonist

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

1.	Fioravanti, Gabriella: 1 article (01/2021)
2.	Hua, Phuong Q: 1 article (01/2021)
3.	Tomlinson, Ryan E: 1 article (01/2021)
4.	Brady, Rhys D: 1 article (01/2018)
5.	Church, Jarrod E: 1 article (01/2018)
6.	Grills, Brian L: 1 article (01/2018)
7.	Johnstone, Maddison R: 1 article (01/2018)
8.	McDonald, Stuart J: 1 article (01/2018)
9.	Shultz, Sandy R: 1 article (01/2018)
10.	Sun, Mujun: 1 article (01/2018)

1.	Leukemia 10/29/2009 - "Moreover, gambogic amide ameliorates the leukemia progression in K562 cells inoculated nude mice. " 10/29/2009 - "Hence, NGF downregulates cyclin A1 expression through escalating CtBP2/acinus complex formation, and gambogic amide might be useful for human leukemia treatment."
2.	Neoplasms (Cancer) 11/08/2023 - "The tumor-enriched small molecule gambogic amide suppresses glioma by targeting WDR1-dependent cytoskeleton remodeling." 11/08/2023 - "In this study, we found a small molecule, gambogic amide (GA-amide), exhibited the ability to effectively penetrate the blood-brain barrier (BBB) and displayed a notable enrichment within the tumor region. "
3.	Stroke (Strokes) 10/09/2007 - "Thus, gambogic amide might not only establish a powerful platform for dissection of the physiological roles of NGF and TrkA receptor but also provide effective treatments for neurodegenerative diseases and stroke."
4.	Neurodegenerative Diseases (Neurodegenerative Disease) 10/09/2007 - "Thus, gambogic amide might not only establish a powerful platform for dissection of the physiological roles of NGF and TrkA receptor but also provide effective treatments for neurodegenerative diseases and stroke."
5.	Wounds and Injuries (Trauma) 11/18/2022 - "Here, we assayed the effects of the partial TrkA agonist Gambogic amide (GA) in peritendinous heterotopic bone after extremity trauma. "