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human MIRN24 microRNA

RefSeq NW_924506.1 (MIR24-1)

Also Known As:

MIRN24 microRNA, human; MIRN24-1 microRNA, human; hsa-mir-24; miR-24, human; miR-24-2, human; miR-24-3p, human; miR24, human; microRNA-24, human

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleic Acids: 11752
  - RNA: 69704
    - Untranslated RNA: 2850
      - Small Untranslated RNA: 566
        MicroRNAs: 67298
        human MIRN24 microRNA: 4
    - Antisense RNA: 1599
      - MicroRNAs: 67298
        human MIRN24 microRNA: 4
- Antisense Elements (Genetics): 31
  - Antisense RNA: 1599
    - MicroRNAs: 67298
      - human MIRN24 microRNA: 4

Experts

1.	Hao, Jian-Ping: 1 article (12/2022)
2.	Qin, Yu-Ting: 1 article (12/2022)
3.	Qu, Jian-Hua: 1 article (12/2022)
4.	Tuerxun, Niluopaer: 1 article (12/2022)
5.	Uddin, Md Nazim: 1 article (12/2022)
6.	Wang, Huan: 1 article (12/2022)
7.	Wang, Jie: 1 article (12/2022)
8.	Zhao, Fang: 1 article (12/2022)
9.	Feng, Xiao-Jun: 1 article (01/2021)
10.	Hu, Xu-Dong: 1 article (01/2021)

Related Diseases

1.	Genetic Translocation (Chromosomal Translocation) 04/01/2013 - "We found that target genes of the most differentially expressed miRNAs are directly involved in the pathogenesis of MM; specifically, the inhibition of hsa-miR-425, hsa-miR-152 and hsa-miR-24, which are all downregulated in h-MM, leads to the overexpression of CCND1, TACC3, MAFB, FGFR3 and MYC, which are the also the oncogenes upregulated by the most frequent IgH chromosomal translocations occurring in nh-MM. Importantly, we showed that the downregulation of these specific miRNAs and the upregulation of their targets also occur simultaneously in primary cases of h-MM. These data provide further evidence on the unifying role of cyclin D pathways deregulation as the key mechanism involved in the development of both groups of MM. Finally, they establish the importance of miRNA deregulation in the context of MM, thereby opening up the potential for future therapeutic approaches based on this molecular mechanism."
2.	Neoplasms (Cancer) 12/01/2022 - "Furthermore, the expression level of CDKN2A is correlated with immune signatures, including CD4+ Regulatory T cells, T cell exhaustion, MHC Class I, immune checkpoint genes, macrophages, neutrophils, and TH2 cells in the TME of MM. Finally, we revealed the consistently deregulated expression level of key gene CDKN2A and its co-regulatory DEmiRs, including hsa-mir-192, hsa-mir-10b, hsa-mir-492, and hsa-mir-24 in the independent cohorts of MM. Identifying key genes and miRNA-mRNA regulatory networks may provide new molecular insights into the tumor immune microenvironment in MM."
3.	Neoplasm Metastasis (Metastasis) 05/18/2015 - "This potential path highlights the crucial role of BMP2, hsa-miR-24, AP2 and MYC as the up-stream regulators of the path and hsa-miR-215 and TYMS as potential indicator of chemotherapeutic benefit in STS metastasis. "
4.	Hepatocellular Carcinoma (Hepatoma) 01/01/2021 - "Bioinformatics analysis of the miRNA transcriptome showed that hsa-miR-24, hsa-miR-6769b-3p, hsa-miR-6836-3p, hsa-miR-199a-3p, hsa-miR-663a, hsa-miR-4739, hsa-miR-6892-3p, hsa-miR-7107-5p, hsa-miR-1273g-3p, hsa-miR-1343, and hsa-miR-6089 were the most significantly up-regulated miRNAs, and their key gene targets were MAPK1, PIK3CD, HRAS, CCND1, CDKN1A, E2F2, etc. The core regulatory pathways of the up-regulated miRNAs were associated with the hepatocellular carcinoma pathway. "

Related Drugs and Biologics

1.	MicroRNAs (MicroRNA)
2.	Cyclin D
3.	Messenger RNA (mRNA)
4.	Indicators and Reagents (Reagents)
5.	human MIRN425 microRNA
6.	human MIRN215 microRNA
7.	human MIRN152 microRNA
8.	human MIRN192 microRNA
9.	human MIRN-1343 microRNA