Calponins

A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.

Also Known As:

Calponin; Calponin Family Proteins

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Microfilament Proteins: 486
      - Calponins: 416
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Calcium-Binding Proteins: 1333
      - Calponins: 416
  - Cytoskeletal Proteins: 739
    - Microfilament Proteins: 486
      - Calponins: 416
  - Contractile Proteins: 699
    - Muscle Proteins: 1582
      - Calponins: 416

human SMTNL1 protein

Bio-Agent Context: Research Results