macranthoside B

Antineoplastic Agent, Phytogenic from Lonicera macranthoides; structure in first source

Also Known As:

3-O-beta-D-glucopyranosyl (1-4)-beta-D-glucopyranosyl (1-3)-alpha-L-rhamnopyranosyl (1-2)-alpha-L-arabinopyranosyl-hederagenin

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Adenocarcinoma 01/01/2022 - "Mechanistic Study of Macranthoside B Effects on Apoptotic Cell Death in Human Cervical Adenocarcinoma Cells."
2.	Neoplasms (Cancer) 01/01/2016 - "Macranthoside B (MB), a saponin compound in Lonicera macranthoides, can block cell proliferation and induce cell death in several types of cancer cells; however, the precise mechanisms by which MB exerts its anticancer effects remain poorly understood. " 07/01/2009 - "Macranthoside B, a hederagenin saponin extracted from Lonicera macranthoides and its anti-tumor activities in vitro and in vivo."
3.	Ovarian Neoplasms (Ovarian Cancer) 01/01/2016 - "Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells."

1.	Saponins
2.	Reactive Oxygen Species (Oxygen Radicals)
3.	hederagenin