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marineosin A

cytotoxic spiroaminal from a marine-derived actinomycete; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - marineosin A: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Spiro Compounds: 2
      - marineosin A: 1
Polycyclic Compounds: 6
- Spiro Compounds: 2
  - marineosin A: 1

Experts

1.	Boonlarppradab, Chollaratt: 1 article (12/2008)
2.	Fenical, William: 1 article (12/2008)
3.	Jensen, Paul R: 1 article (12/2008)
4.	Kauffman, Christopher A: 1 article (12/2008)

Related Diseases

1.	Neoplasms (Cancer) 12/18/2008 - "The marineosins, which appear to be derived from unknown modifications of prodigiosin-like pigment pathways, showed significant inhibition of human colon carcinoma (HCT-116) in an in vitro assay (IC50 = 0.5 microM for marineosin A) and selective activities in diverse cancer cell types."
2.	Carcinoma (Carcinomatosis) 12/18/2008 - "The marineosins, which appear to be derived from unknown modifications of prodigiosin-like pigment pathways, showed significant inhibition of human colon carcinoma (HCT-116) in an in vitro assay (IC50 = 0.5 microM for marineosin A) and selective activities in diverse cancer cell types."

Related Drugs and Biologics

1.	Prodigiosin