|1.||Mazar, Andrew P: 4 articles (01/2014 - 07/2009)|
|2.||Shaw, David E: 2 articles (02/2011 - 10/2010)|
|3.||Meehan, Edward J: 1 article (01/2014)|
|4.||Dubrovskyi, Oleksii: 1 article (01/2014)|
|5.||Ugolkov, Andrey: 1 article (01/2014)|
|6.||Juarez, Jose: 1 article (01/2014)|
|7.||Cai, Yuan: 1 article (01/2014)|
|8.||Donate, Fernando: 1 article (01/2014)|
|9.||Parry, Graham: 1 article (01/2014)|
|10.||Huang, Mingdong: 1 article (01/2014)|
10/01/2010 - "Results from these studies provide compelling evidence for the continued development of ATN-658 as a potential therapeutic agent for the treatment of prostate and other cancers expressing uPAR."
10/01/2010 - "In in vivo studies, ATN-658 caused a significant decrease in tumor volume and a marked reduction in skeletal lesions as determined by Faxitron x-ray and micro-computed tomography. "
07/15/2009 - "ATN-658 significantly inhibited in vivo tumor cell proliferation in both studies. "
01/01/2014 - "Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM)."
07/15/2009 - "In vivo, ATN-658 lead to significant reductions in tumor growth versus control when initiated either 4 or 12 days after tumor implantation (-65% vs control [P < or = .05] and -85% vs control [P < or = .05]). "
|2.||Prostatic Neoplasms (Prostate Cancer)
|3.||Ovarian Neoplasms (Ovarian Cancer)
02/01/2011 - "This provides a rationale for targeting the u-PAR pathway in patients with ovarian cancer and for further testing of ATN-658 in this indication."
02/01/2011 - "The impact of the u-PAR antibody on tumor weight, number, and survival was examined in corresponding ovarian cancer xenograft models and the mechanism by which ATN-658 blocks metastasis was explored. "
|4.||Neoplasm Metastasis (Metastasis)
|1.||Complementarity Determining Regions (Complementarity Determining Region)
|2.||Immunoglobulin G (IgG)
|4.||Complement System Proteins (Complement)
|1.||Heterologous Transplantation (Xenotransplantation)