HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

OTR 4131

RGTA - ReGeneraTing agent; a heparan mimetic; structure in first source

Also Known As:

OTR-4131; OTR4131; RGTA-OTR4131

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Glucans: 1624
      - OTR 4131: 1
Carbohydrates: 22023
- Polysaccharides: 15383
  - Glucans: 1624
    - OTR 4131: 1

Experts

1.	Auperin, Anne: 1 article (07/2009)
2.	Barritault, Denis: 1 article (07/2009)
3.	Biti, Giampaolo: 1 article (07/2009)
4.	Bourhis, Jean: 1 article (07/2009)
5.	Castaing, Marine: 1 article (07/2009)
6.	Deutsch, Eric: 1 article (07/2009)
7.	Frascogna, Valerie: 1 article (07/2009)
8.	Mangoni, Monica: 1 article (07/2009)
9.	Morin, Christophe: 1 article (07/2009)
10.	Opolon, Paule: 1 article (07/2009)

Related Diseases

1.	Stomatitis 07/15/2009 - "Therefore, we investigated the protective efficacy of a new heparan mimetic biopolymer, RGTA-OTR4131, used alone or in combination with amifostine, for oral mucositis and simultaneously evaluated its effect on tumor growth in vitro and in vivo. "
2.	Neoplasms (Cancer) 07/15/2009 - "The effect of OTR4131 administration on tumor growth was then investigated in vitro and in xenograft models using two cell lines (HEP-2 and HT-29). " 07/15/2009 - "At the tumor level, OTR4131 did not modify HEP-2 cell line clonogenic survival in vitro or protect xenografted tumor cells from radiotherapy. " 07/15/2009 - "Therefore, we investigated the protective efficacy of a new heparan mimetic biopolymer, RGTA-OTR4131, used alone or in combination with amifostine, for oral mucositis and simultaneously evaluated its effect on tumor growth in vitro and in vivo. "

Related Drugs and Biologics

1.	Amifostine (Ethyol)
2.	Biopolymers (Biopolymer)

Related Therapies and Procedures

1.	Radiotherapy