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cudraflavone B

antiproliferative from Cudrania tricuspidata

Networked: 6 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        cudraflavone B: 6
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        cudraflavone B: 6

Experts

1.	Kim, Youn-Chul: 2 articles (07/2014 - 09/2013)
2.	Lee, Dong-Sung: 2 articles (07/2014 - 09/2013)
3.	Jeong, Gil-Saeng: 1 article (07/2014)
4.	Kim, Dong-Cheol: 1 article (07/2014)
5.	Ko, Wonmin: 1 article (07/2014)
6.	Auh, Q-Schick: 1 article (09/2013)
7.	Chang, Seok-Woo: 1 article (09/2013)
8.	Kang, Soo-Kyung: 1 article (09/2013)
9.	Kim, Eun-Cheol: 1 article (09/2013)
10.	Lee, Hwa-Jeong: 1 article (09/2013)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2023 - "The natural product Cudraflavone B (CUB) has been reported to potentially kill a variety of tumor cells. " 01/01/2013 - "From the three compounds tested, cudraflavone B showed the strongest effects on cell cycle progression and viability of tumor and/or immortalized cells and also on inflammatory response of macrophage-like cells. " 01/01/2013 - "The aim of this study was to evaluate cytotoxicity of three flavonoids isolated from MA (kuwanon E, cudraflavone B, and 4'-O-methylkuwanon E) and to determine their effects on proliferation of THP-1 cells, and on cell cycle progression of cancer cells. "
2.	Squamous Cell Carcinoma of Head and Neck 09/01/2013 - "Therefore, cudraflavone B may be a lead for the development of a potential candidate for human oral squamous cell carcinoma cells. " 09/01/2013 - "The goal of this study was to investigate the effect and molecular mechanism of cudraflavone B, a prenylated flavonoid isolated from the root bark of Cudrania tricuspidata, against oral squamous cell carcinoma cells. "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 07/24/2014 - "Our results demonstrated the potential application of naturally occurring cudraflavone B as a therapeutic agent from neurodegenerative disease. "
4.	Mouth Neoplasms (Oral Cancer) 09/01/2013 - "Growth inhibition and apoptosis-inducing effects of cudraflavone B in human oral cancer cells via MAPK, NF-κB, and SIRT1 signaling pathway."
5.	Experimental Melanoma 09/01/2011 - "In the in vitro assay, using B16 melanoma cells, the prenylated polyphenols isolated from Artocarpus plants, such as artocarpin, cudraflavone C, 6-prenylapigenin, kuwanon C, norartocarpin, albanin A, cudraflavone B, and brosimone I showed potent inhibitory activity on melanin formation. "

Related Drugs and Biologics

1.	Flavonoids
2.	Polyphenols
3.	Sirtuin 1
4.	Melanins (Melanin)
5.	Gibberellins
6.	6-prenylapigenin
7.	liquiritin
8.	neoisoliquiritin
9.	artocarpin lectin
10.	Mulberrin