eusynstyelamide B

nNOS inhibitor from the ascidian Eusynstyela latericius; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 12/22/2015 - "As part of an anti-cancer natural product drug discovery program, we recently identified eusynstyelamide B (EB), which displayed cytotoxicity against MDA-MB-231 breast cancer cells (IC50 = 5 μM) and induced apoptosis. "
2.	Breast Neoplasms (Breast Cancer) 12/22/2015 - "As part of an anti-cancer natural product drug discovery program, we recently identified eusynstyelamide B (EB), which displayed cytotoxicity against MDA-MB-231 breast cancer cells (IC50 = 5 μM) and induced apoptosis. " 12/22/2015 - "The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells."

1.	Poisons
2.	Type II DNA Topoisomerases (Topoisomerase II)