pterodontic acid

anti-bacterial from Laggera pterodonta; structure in first source

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

1.	Virus Diseases (Viral Diseases) 07/01/2021 - "In this manuscript, a series of pterodontic acid derivatives were prepared and demonstrated significantly improved anti-influenza A virus (H1N1) activities, providing more opportunities for the treatment of respiratory viral diseases."
2.	Infections 12/01/2019 - "The interferon system was also affected, the STAT1, IFN-α, IFN-β expression were also inhibited by pterodontic acid at 25-100 μg/ml and also, the important programmed death-ligand of PD-L1 and PD-L2 was inhibited at 50-100 μg/ml. The mechanisms of pterodontic acid against influenza virus infection may be a cascade inhibition and it has the anti-inflammatory activity, which has no side effect, and can be as a supplement drug in clinical influenza virus infection." 07/01/2018 - "An active component containing pterodontic acid and pterodondiol isolated from Laggera pterodonta inhibits influenza A virus infection through the TLR7/MyD88/TRAF6/NF‑κB signaling pathway."
3.	Inflammation (Inflammations) 10/16/2017 - "Pterodontic Acid Isolated from Laggera pterodonta Inhibits Viral Replication and Inflammation Induced by Influenza A Virus."

1.	TNF Receptor-Associated Factor 6 (TRAF6)
2.	Ligands
3.	Interferons
4.	pterodondiol