|1.||Avilés, Pablo: 4 articles (01/2014 - 04/2009)|
|2.||Cuevas, Carmen: 4 articles (01/2014 - 04/2009)|
|3.||Hornicek, Francis J: 3 articles (06/2010 - 01/2009)|
|4.||Choy, Edwin: 3 articles (06/2010 - 01/2009)|
|5.||Duan, Zhenfeng: 3 articles (06/2010 - 01/2009)|
|6.||Moneo, Victoria: 2 articles (01/2014 - 07/2009)|
|7.||Fernández Teruel, Carlos: 2 articles (11/2012 - 01/2012)|
|8.||Valenzuela, Belén: 2 articles (11/2012 - 01/2012)|
|9.||Soto-Matos, Arturo: 2 articles (11/2012 - 01/2012)|
|10.||Pérez-Ruixo, Carlos: 2 articles (11/2012 - 01/2012)|
07/15/2009 - "Molecular pharmacology and antitumor activity of Zalypsis in several human cancer cell lines."
04/16/2009 - "The potent in vitro and in vivo antimyeloma activity of Zalypsis uncovers the high sensitivity of tumor plasma cells to DSBs and strongly supports the use of this compound in MM patients."
01/01/2013 - "Phase II study of weekly PM00104 (ZALYPSIS(®)) in patients with pretreated advanced/metastatic endometrial or cervical cancer."
01/01/2012 - "The aim of this study was to characterize the population pharmacokinetics of PM00104 (Zalypsis(®)) in cancer patients. "
01/01/2014 - "The identification of biomarkers for Zalypsis activity would also contribute to broaden the spectrum of tumors by selecting those patients more likely to respond to this therapy. "
|2.||Endometrial Neoplasms (Endometrial Cancer)
|3.||Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
05/01/2011 - "The potent and selective antileukemic effect of zalypsis on DNA damage response mechanisms observed in acute myeloid leukemia cell lines and in patients' samples provides the rationale for the investigation of this compound in clinical trials."
05/01/2011 - "The activity of zalypsis was studied in four acute myeloid leukemia cell lines and in freshly isolated blasts taken from patients with acute myeloid leukemia before they started therapy. "
|4.||Ewing's Sarcoma (Sarcoma, Ewing)
|2.||trabectedin (ecteinascidin 743)
|3.||Biological Markers (Surrogate Marker)
|4.||Protein-Tyrosine Kinases (Tyrosine Kinase)
|2.||Drug Therapy (Chemotherapy)
|3.||Heterologous Transplantation (Xenotransplantation)