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neosergeolide

isolated from the Amazonian medicinal plant Picrolemma sprucei (Simaroubaceae)

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Quassins: 86
        neosergeolide: 1

Experts

1.	Amorim, Rodrigo C N: 1 article (08/2012)
2.	Carvalho, Adriana A: 1 article (08/2012)
3.	Cavalcanti, Bruno C: 1 article (08/2012)
4.	Costa-Lotufo, Letícia V: 1 article (08/2012)
5.	Moraes, Manoel O: 1 article (08/2012)
6.	Pessoa, Cláudia: 1 article (08/2012)
7.	Pohlit, Adrian M: 1 article (08/2012)
8.	Rodrigues, Felipe A R: 1 article (08/2012)
9.	Silva, Ellen C C: 1 article (08/2012)
10.	da Costa, Patrícia M: 1 article (08/2012)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2012 - "After 24 h exposure, neosergeolide strongly inhibited cancer cell proliferation (IC₅₀ 0.1 µM), and its activity seemed to be selective to tumor cells because it had no antiproliferative effect on human peripheral blood mononuclear cells (PBMC) at tested concentrations. "
2.	Leukemia 08/01/2012 - "Involvement of intrinsic mitochondrial pathway in neosergeolide-induced apoptosis of human HL-60 leukemia cells: the role of mitochondrial permeability transition pore and DNA damage."

Related Drugs and Biologics

1.	Mitochondrial Permeability Transition Pore