|1.||Krajewski, Stan: 3 articles (01/2013 - 04/2009)|
|2.||De, Surya K: 3 articles (01/2013 - 04/2009)|
|3.||Pellecchia, Maurizio: 3 articles (01/2013 - 04/2009)|
|4.||Barile, Elisa: 2 articles (01/2013 - 08/2011)|
|5.||Feng, Yongmei: 2 articles (01/2013 - 08/2011)|
|6.||Ronai, Ze'ev A: 2 articles (01/2013 - 08/2011)|
|7.||Aza-Blanc, Pedro: 2 articles (01/2013 - 08/2011)|
|8.||Pal, Ipsita: 1 article (10/2015)|
|9.||Chakraborty, Sandipan: 1 article (10/2015)|
|10.||Banik, Payel: 1 article (10/2015)|
|1.||Melanoma (Melanoma, Malignant)
01/01/2013 - "Here we extend our earlier studies where we demonstrated that the small molecule BI-69A11 inhibits the growth of melanoma cell lines. "
07/08/2014 - "BI-69A11, a small molecule inhibitor of Akt, efficiently inhibits growth in melanoma cells. "
01/01/2013 - "The ability to attenuate the development of NRAS mutant melanomas supports further development of BI-69A11 for clinical assessment."
01/01/2013 - "Biweekly administration of BI-69A11 starting at 10 weeks or as late as 24 weeks after the induction of mutant Nras expression inhibited melanoma development (100 and 36%, respectively). "
01/01/2013 - "Strikingly, the administration of BI-69A11 inhibited melanoma development in genetically modified mice bearing an inducible form of activated Nras and a deletion of the Ink4a gene (Nras((Q61K)) ::Ink4a(-/-) ). "
01/01/2013 - "BI-69A11 treatment did not inhibit the development of histiocytic sarcomas, which constitute about 50% of the tumors in this model. "
04/01/2009 - "Analysis of BI-69A11 was performed in melanoma cells, a tumor type that commonly exhibits up-regulation of AKT. "
04/01/2009 - "These findings identify BI-69A11 as a potent inhibitor of AKT that is capable of eliciting effective regression of xenograft melanoma tumors."
04/01/2009 - "Significantly, intra-peritoneal injection of BI-69A11 caused effective regression of melanoma tumor xenografts, which coincided with elevated levels of cell death. "
|3.||Colonic Neoplasms (Colon Cancer)
10/15/2015 - "In summary; our findings suggest that induction of autophagy lead to the resistance of colon cancer towards BI-69A11 mediated apoptosis. "
07/08/2014 - "BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt."
10/15/2015 - "BI-69A11, novel Akt inhibitor, is currently drawing much attention due to its intriguing effect in inducing apoptosis in melanoma, breast, prostate and colon cancer. "
|1.||Heterologous Transplantation (Xenotransplantation)