|1.||Cao, Jian-Guo: 3 articles (01/2015 - 07/2006)|
|2.||Wang, Cheng-Kun: 1 article (01/2015)|
|3.||Zhang, Zhi-Jie: 1 article (01/2015)|
|4.||He, Zhi-Min: 1 article (01/2015)|
|5.||Qiu, Qin-Wei: 1 article (01/2015)|
|6.||Zhang, Yang: 1 article (01/2015)|
|7.||He, Zhi-min: 1 article (06/2010)|
|8.||Gu, Yi-xue: 1 article (06/2010)|
|9.||Peng, Bo: 1 article (06/2010)|
|10.||Cao, Jian-guo: 1 article (06/2010)|
04/14/2009 - "rVBMDMP has effective and unique anti-tumor properties, and is a promising candidate for the development of anti-tumor drugs."
04/14/2009 - "rVBMDMP (1, 3, 10 mg/kg) decreased the tumor weight by 12.6%, 55.9% and 79.7%, respectively, compared with the vehicle control. "
07/01/2006 - "These results suggest that rVBMDMP is a powerful therapeutic agent for suppressing angiogenesis and tumor growth."
07/01/2006 - "Vascular basement membrane-derived multifunctional peptide, a novel inhibitor of angiogenesis and tumor growth."
04/14/2009 - "rVBMDMP at doses of 1, 3 and 10 mg/kg significantly reduced the tumor microvessel area levels (0.26% +/- 0.07%, 0.12% +/- 0.03% and 0.05% +/- 0.01% vs 0.45% +/- 0.15%) in HepG2 xenografts (P < 0.01), as assessed by CD31 staining. "
|2.||Lewis Lung Carcinoma
07/01/2006 - "Recombinant VBMDMP produced in Escherichia coli has been shown to have significant activity of antitumor growth and antimetastasis in Lewis lung carcinoma transplanted into mouse C57Bl/6. In the present study, we have studied the ability of rVBMDMP to inhibit endothelial cell tube formation and proliferation, to induce apoptosis in vitro, and to suppress tumor growth in vivo. "
|3.||Lung Neoplasms (Lung Cancer)
01/01/2015 - "The present study further systematically observed the inhibitory effect of rVBMDMP on lung cancer cell growth and analyzed a possible mechanism to provide a theoretical basis for the development of new antitumor protein drugs. "
01/01/2015 - "Effects of VBMDMP on the reversal of cisplatin resistance in human lung cancer A549/DDP cells."
01/01/2015 - "A lung cancer xenograft model was used to evaluate the reversal effect of rVBMDMP on drug-resistance of A549/DDP cell tumors to cisplatin in vivo. "
06/28/2010 - "The aim of this study is to explore the effects and mechanisms of rVBMDMP on growth and motility/invasion in human A549 lung carcinoma cells. "
06/28/2010 - "These findings contribute to the understanding of the molecular mechanisms mediating rVBMDMP action, and suggest that rVBMDMP is a promising novel agent for the treatment of human lung carcinoma."
|5.||Hepatocellular Carcinoma (Hepatoma)
04/14/2009 - "Recombinant vascular basement-membrane-derived multifunctional peptide inhibits angiogenesis and growth of hepatocellular carcinoma."
04/14/2009 - "To investigate the anti-angiogenic and anti-tumor activities of recombinant vascular basement membrane-derived multifunctional peptide (rVBMDMP) in hepatocellular carcinoma (HCC). "
|1.||vascular basement membrane-derived multifunctional peptide
|2.||Complementary DNA (cDNA)
|1.||Heterologous Transplantation (Xenotransplantation)