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6- methoxy- 9- methyl- (1,3)dioxolo(4,5- h)quinolin- 8(9H)- one

a quinone reductase 2 inhibitor; isolated from Casimiroa edulis; structure in first source

Also Known As:

casimiroin

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxoles
    - Benzodioxoles: 3
      - 6-methoxy-9-methyl-(1,3)dioxolo(4,5-h)quinolin-8(9H)-one: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolones: 2938
        6-methoxy-9-methyl-(1,3)dioxolo(4,5-h)quinolin-8(9H)-one: 1
    - Benzodioxoles: 3
      - 6-methoxy-9-methyl-(1,3)dioxolo(4,5-h)quinolin-8(9H)-one: 1

Experts

1.	Gao, Mingzhang: 1 article (12/2010)
2.	Hutchins, Gary D: 1 article (12/2010)
3.	Miller, Kathy D: 1 article (12/2010)
4.	Sledge, George W: 1 article (12/2010)
5.	Wang, Min: 1 article (12/2010)
6.	Zheng, Qi-Huang: 1 article (12/2010)

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

12/01/2010 - "Carbon-11-labeled casimiroin analogues were first designed and synthesized as new potential PET agents for imaging of quinone reductase (QR) 2 and aromatase expression in breast cancer. "
12/01/2010 - "Synthesis of carbon-11-labeled casimiroin analogues as new potential PET agents for imaging of quinone reductase 2 and aromatase expression in breast cancer."

Related Drugs and Biologics

1.	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
2.	Aromatase (CYP19)