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((1S,2S,4R)- 4- (4- ((1S)- 2,3- dihydro- 1H- inden- 1- ylamino)- 7H- pyrrolo(2,3- d)pyrimidin- 7- yl)- 2- hydroxycyclopentyl)methyl sulphamate

a potent and selective inhibitor of NAE (NEDD8-activating enzyme)
Also Known As:
((1S,2S,4R)-4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl)methyl sulfamate; 4-(4-((1S)-2,3-dihydro-1H-inden-1-ylamino)-7H-pyrrolo(2,3-d)pyrimidin-7-yl)-2-hydroxycyclopentyl methyl sulfamidate; MLN4924
Networked: 61 relevant articles (8 outcomes, 20 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Smith, Peter G: 13 articles (01/2015 - 05/2010)
2. Sun, Yi: 12 articles (12/2014 - 01/2011)
3. Jia, Lijun: 11 articles (10/2015 - 06/2011)
4. Jeong, Lak Shin: 7 articles (04/2015 - 07/2012)
5. Milhollen, Michael A: 7 articles (10/2013 - 01/2010)
6. Chu, Yiwei: 5 articles (10/2015 - 07/2012)
7. Wei, Dongping: 5 articles (04/2015 - 01/2012)
8. Zhao, Yongchao: 5 articles (12/2014 - 05/2012)
9. Narayanan, Usha: 5 articles (01/2013 - 09/2010)
10. Li, Chunjie: 4 articles (10/2015 - 01/2014)

Related Diseases

1. Neoplasms (Cancer)
2. Liver Neoplasms (Liver Cancer)
3. Stomach Neoplasms (Stomach Cancer)
4. Ovarian Neoplasms (Ovarian Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Cisplatin (Platino)
2. Platinum
3. Chloroquine (Aralen)
4. Proteins (Proteins, Gene)
5. Ubiquitin
6. DNA (Deoxyribonucleic Acid)
7. Angiogenesis Inhibitors
8. Dextran Sulfate
9. Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
10. Ligases

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Aftercare (After-Treatment)