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(4- amino- 1- (4- chlorobenzyl)- 2- methyl- 5- phenyl- 1H- pyrrol- 3- yl)(phenyl)methanone

structure in first source

Also Known As:

URB447

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        (4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - (4-amino-1-(4-chlorobenzyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)(phenyl)methanone: 3

Experts

1.	Duranti, Andrea: 2 articles (01/2020 - 02/2009)
2.	Piomelli, Daniele: 2 articles (01/2020 - 02/2009)
3.	Alonso-Alconada, Daniel: 1 article (01/2020)
4.	Balduini, Walter: 1 article (01/2020)
5.	Carloni, Silvia: 1 article (01/2020)
6.	Crinelli, Rita: 1 article (01/2020)
7.	Palma, Linda: 1 article (01/2020)
8.	Álvarez, Francisco J: 1 article (01/2020)
9.	LoVerme, Jesse: 1 article (02/2009)
10.	Mor, Marco: 1 article (02/2009)

Related Diseases

1.	Neoplasm Metastasis (Metastasis) 09/20/2022 - "Moreover, daily treatment of tumor bearing mice with URB447 decreased the development of liver metastasis in a melanoma model in vivo. " 09/20/2022 - "This proof of concept study points out to the synthetic cannabinoid URB447 as a potential candidate for deeper studies to confirm its potential as antitumor therapy and liver metastasis treatment for CRC and melanoma."
2.	Melanoma (Melanoma, Malignant) 09/20/2022 - "Moreover, daily treatment of tumor bearing mice with URB447 decreased the development of liver metastasis in a melanoma model in vivo. " 09/20/2022 - "The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer." 09/20/2022 - "This proof of concept study points out to the synthetic cannabinoid URB447 as a potential candidate for deeper studies to confirm its potential as antitumor therapy and liver metastasis treatment for CRC and melanoma."
3.	Neoplasms (Cancer) 09/20/2022 - "Moreover, daily treatment of tumor bearing mice with URB447 decreased the development of liver metastasis in a melanoma model in vivo. "
4.	Experimental Melanoma 09/20/2022 - "We used the synthetic cannabinoid URB447, a known CB2 agonist and CB1 antagonist drug, and studied prometastatic ability of mouse B16 melanoma and MCA38 CRC cells, by means of proliferation, apoptosis, cell cycle, migration and matrix degradation in vitro upon URB447 treatment. "
5.	Ischemia 01/01/2020 - "By using a model of hypoxia-ischemia (HI) in neonatal rats, we found that URB447 strongly reduced brain injury when administered before HI. " 01/01/2020 - "The Synthetic Cannabinoid URB447 Reduces Brain Injury and the Associated White Matter Demyelination after Hypoxia-Ischemia in Neonatal Rats."

Related Drugs and Biologics

1.	Cannabinoids
2.	Cannabinoid Receptor Antagonists

Related Therapies and Procedures

1.	Therapeutics