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HCV 796

inhibits HCV RdRp; structure in first source

Also Known As:

HCV-796; HCV796

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - HCV 796: 2
Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - HCV 796: 2
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - HCV 796: 2

Experts

1.	Buck, Martina: 1 article (04/2009)
2.	Feldstein, Ariel: 1 article (04/2009)
3.	Kleiner, David: 1 article (04/2009)
4.	Kravetz, David: 1 article (04/2009)
5.	Bard, Joel: 1 article (09/2008)
6.	Cheng, Huiming: 1 article (09/2008)
7.	Chopra, Rajiv: 1 article (09/2008)
8.	Chunduru, Srinivas K: 1 article (09/2008)
9.	Howe, Anita Y M: 1 article (09/2008)
10.	Johann, Stephen: 1 article (09/2008)

Related Diseases

1.	Hepatitis C 04/01/2009 - "HCV-796 is a hepatitis C polymerase inhibitor approved by the US Food and Drug Administration for a phase 2 study of the treatment of hepatitis C in combination with PEG-Interferon and ribavirin. "
2.	Hepatocellular Carcinoma (Hepatoma) 09/01/2008 - "In hepatoma cells containing a genotype 1b HCV replicon, HCV-796 reduced HCV RNA levels by 3 to 4 log(10) HCV copies/mug total RNA (the concentration of the compound that inhibited 50% of the HCV RNA level was 9 nM). "

Related Drugs and Biologics

1.	Ribavirin (Virazole)
2.	Interferons
3.	RNA (Ribonucleic Acid)