|1.||Muanda, Tsobo: 2 articles (06/2012 - 02/2012)|
|2.||Cimanga, Kanyanga: 2 articles (06/2012 - 02/2012)|
|3.||Mampunza, Ma Miezi: 2 articles (06/2012 - 02/2012)|
|4.||Mets, Tony: 2 articles (06/2012 - 02/2012)|
|5.||Mesia, Kahunu: 2 articles (06/2012 - 02/2012)|
|6.||Muyembe, Tamfum: 2 articles (06/2012 - 02/2012)|
|7.||Ntamabyaliro, Nsengi: 2 articles (06/2012 - 02/2012)|
|8.||Pieters, Luc: 2 articles (06/2012 - 02/2012)|
|9.||Tona, Lutete: 2 articles (06/2012 - 02/2012)|
|10.||Vlietinck, Arnold J: 2 articles (06/2012 - 02/2012)|
|1.||Falciparum Malaria (Plasmodium falciparum Malaria)
06/01/2012 - "According to the promising results of the Phase I and Phase IIA clinical trials with the herbal medicinal product PR 259 CT1 consisting of an 80 % ethanolic extract of the stem bark of Nauclea pobeguinii containing 5.6 % strictosamide, a Phase IIB study was conducted as a single blind prospective trial in 65 patients with proven Plasmodium falciparum malaria to evaluate the effectiveness and safety of this herbal drug. "
02/01/2012 - "The aim of this phase IIA clinical trial was to assess the efficacy of an 80 % ethanolic quantified extract (containing 5.6 % strictosamide as the putative active constituent) from Nauclea pobeguinii stem bark denoted as PR 259 CT1 in a small group of adult patients diagnosed with uncomplicated falciparum malaria. "
10/01/1999 - "Bioassay-guided fractionation of the organic extracts of whole plants of Mostuea brunonis (Loganiaceae), using the National Cancer Institute's (NCI) human tumor-based in vitro antitumor screen, led to the isolation and identification of camptothecin 20-O-beta-D-glucoside (1) and three moderately cytotoxic alkaloids, the known deoxypumiloside (2) and strictosamide (3), and the new 2'-O-acetylstrictosamide (4), from the cytotoxic alkaloid fractions. "
01/01/2015 - "This work was designed to assess the cytotoxicity of six selected Cameroonian medicinal plants, including Nauclea pobeguinii and its constituents 3-acetoxy-11-oxo-urs-12-ene (1), p-coumaric acid (2), citric acid trimethyl ester (3), resveratrol (4), resveratrol β- D -glucopyranoside (5) and strictosamide (6), against 8 drug-sensitive and multidrug-resistant (MDR) cancer cell lines. "
11/01/2014 - "Strictosamide may have important effects on inflammation and inflammatory pain. "
11/01/2014 - "Strictosamide is the main representative constituent of Nauclea officinalis Pierre ex Pitard (Rubiaceae), which has been used for a long time in China to treat diseases related to infection and inflammation, but its pharmacological activities are not well studied. "
|1.||Citric Acid (Citrate)
|2.||Acetic Acid (Vinegar)
|5.||Adenosine Triphosphatases (ATPase)
|7.||4-coumaric acid (p-coumaric acid)