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fargesin

isolated from Magnoliae flos; structure in first source

Also Known As:

1,3-Benzodioxole, 5-((1S,3aR,4R,6aR)-4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-

Networked: 14 relevant articles (4 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzyl Compounds: 2
        Lignans: 1113
        fargesin: 14
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Dioxoles
    - Benzodioxoles: 3
      - fargesin: 14
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzodioxoles: 3
      - fargesin: 14

Experts

1.	Oh, Sei-Ryang: 2 articles (02/2021 - 01/2017)
2.	Li, Xiaoni: 2 articles (08/2016 - 09/2015)
3.	Son, Kun Ho: 2 articles (02/2014 - 10/2009)
4.	An, Hyun-Jung: 1 article (02/2021)
5.	Cho, Sung-Jun: 1 article (02/2021)
6.	Cho, Yong-Yeon: 1 article (02/2021)
7.	Kang, Han Chang: 1 article (02/2021)
8.	Kim, Dae Joon: 1 article (02/2021)
9.	Lee, Cheol-Jung: 1 article (02/2021)
10.	Lee, Ga-Eun: 1 article (02/2021)

Related Diseases

1.	Lung Injury 11/01/2022 - "The aim of this study was to figure out the possible effectiveness of the fargesin, and to invest the mechanisms by which it works in the cadmium-induced lung injury in mice. " 11/01/2022 - "In conclusion, fargesin attenuates cadmium-induced lung injury may be via activating AhR, which subsequently suppressing the inflammatory response." 11/01/2022 - "Protective effects of fargesin on cadmium-induced lung injury through regulating aryl hydrocarbon receptor."
2.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/07/2018 - "We sought to investigate whether fargesin ameliorates experimental inflammatory bowel disease (IBD) in mice. " 06/07/2018 - "Anti-Inflammatory Effects of Fargesin on Chemically Induced Inflammatory Bowel Disease in Mice."
3.	Pulmonary Edema 11/01/2022 - "Fargesin dose-dependently reduced inflammatory cells and pro-inflammatory cytokines in BALF, improved lung histopathological injury, and inhibited lung wet/dry ratio and MPO activity. "
4.	Osteoarthritis 01/01/2021 - "Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways." 01/01/2021 - "To investigate the role and regulatory mechanisms of fargesin, one of the main components of Magnolia fargesii, in macrophage reprogramming and crosstalk across cartilage and synovium during osteoarthritis (OA) development. " 01/01/2021 - "Fargesin attenuated articular cartilage degeneration and synovitis, resulting in substantially lower Osteoarthritis Research Society International (OARSI) and synovitis scores. "
5.	Body Weight (Weight, Body) 07/01/2012 - "In HFD-induced obese mice, fargesin decreased the body weight gain, white adipose tissue (WAT), and plasma triglyceride, non-esterified fatty acid and glucose levels, and improved the glucose tolerance. "

Related Drugs and Biologics

1.	Cadmium
2.	Cytokines
3.	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
4.	Triglycerides (Triacylglycerol)
5.	Glucose (Dextrose)
6.	Fatty Acids (Saturated Fatty Acids)
7.	Lignans
8.	Messenger RNA (mRNA)
9.	magnolin
10.	lirioresinol B dimethyl ether

Related Therapies and Procedures

1.	East Asian Traditional Medicine (Oriental Medicine)
2.	Oral Administration