HLA-DPB1*05:01 antigen

Also Known As:

HLA DPB1*0501; HLA DPB1*05:01 antigen; HLA-DPB1*0501

Networked: 10 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10
  - Isoantigens: 1221
    - Histocompatibility Antigens: 1132
      - HLA Antigens: 8934
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10
      - Histocompatibility Antigens Class II: 2170
        HLA-D Antigens: 238
        HLA-DP Antigens: 300
        HLA-DP beta-Chains
        HLA-DPB1*05:01 antigen: 10

Experts

1.	Kira, Jun-ichi: 2 articles (08/2003 - 02/2003)
2.	Isobe, N: 1 article (02/2009)
3.	Kawano, Y: 1 article (02/2009)
4.	Kira, J: 1 article (02/2009)
5.	Matsuoka, T: 1 article (02/2009)
6.	Matsushita, T: 1 article (02/2009)
7.	Minohara, M: 1 article (02/2009)
8.	Nishimura, Y: 1 article (02/2009)
9.	Ochi, H: 1 article (02/2009)
10.	Shi, N: 1 article (02/2009)

Related Diseases

1.	Opticospinal Multiple Sclerosis 09/01/1999 - "HLA-DPB10501-associated opticospinal multiple sclerosis: clinical, neuroimaging and immunogenetic studies." 02/01/2006 - "HLA-dPB10501 is not uniquely associated with opticospinal multiple sclerosis in Japanese patients. " 09/01/1999 - "The frequency of the HLA-DPB10501 allele was found to be significantly greater in opticospinal multiple sclerosis (93%) than in healthy controls (63%, corrected P value = 0.0091 and relative risk = 7.9), but not in Western type multiple sclerosis (66%) or spinal multiple sclerosis (82%). " 09/01/1999 - "The marked differences in the clinical and MRI findings as well as in the immunogenetic backgrounds between the opticospinal multiple sclerosis and Western-type multiple sclerosis together suggest that HLA-DPB10501-associated opticospinal multiple sclerosis is a distinct subtype of multiple sclerosis." 08/01/2003 - "Conventional MS in Japanese is, like MS in Caucasians, associated with HLA-DRB11501 whereas opticospinal MS is associated with HLA-DPB10501. "
2.	Multiple Sclerosis 02/01/2006 - "Apart from its unique lesion distribution pattern, the opticospinal form of multiple sclerosis (OSMS) is distinct among Japanese patients who satisfy the diagnostic criteria of MS. OSMS has been suggested to be strongly associated with HLA-DPB10501 in Japanese. " 09/01/1999 - "The frequency of the HLA-DPB10501 allele was found to be significantly greater in opticospinal multiple sclerosis (93%) than in healthy controls (63%, corrected P value = 0.0091 and relative risk = 7.9), but not in Western type multiple sclerosis (66%) or spinal multiple sclerosis (82%). " 09/01/1999 - "The marked differences in the clinical and MRI findings as well as in the immunogenetic backgrounds between the opticospinal multiple sclerosis and Western-type multiple sclerosis together suggest that HLA-DPB1*0501-associated opticospinal multiple sclerosis is a distinct subtype of multiple sclerosis."
3.	Leukocytosis (Pleocytosis) 01/15/2007 - "IFNB-1b should not be administered to demyelinating patients with genetic and clinical characteristics mimicking NMO such as HLA DPB1*0501 allele, longitudinally extensive spinal cord lesion, blindness and CSF pleocytosis even if they have symptomatic cerebral lesions as typically seen in MS. The present study strongly suggests that these patients should be diagnosed as having NMO."
4.	Blindness (Hysterical Blindness) 01/15/2007 - "IFNB-1b should not be administered to demyelinating patients with genetic and clinical characteristics mimicking NMO such as HLA DPB1*0501 allele, longitudinally extensive spinal cord lesion, blindness and CSF pleocytosis even if they have symptomatic cerebral lesions as typically seen in MS. The present study strongly suggests that these patients should be diagnosed as having NMO."
5.	Graves Disease (Basedow Disease) 01/01/1995 - "HLA-DPB10501 was increased (92.9% vs. 54.3%, P < 0.05, RR: 11.0, chi 2:6.57) in the patients with Graves' disease. " 03/01/1994 - "Association of HLA-DPB10501 with early-onset Graves' disease in Japanese."

Related Drugs and Biologics

1.	HLA-DRB1 Chains (HLA DRB1)
2.	Peptides (Polypeptides)
3.	HLA Antigens (Human Leukocyte Antigens)