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HhAntag691

inhibits the hedgehog pathway and ABC transporters; has antineoplastic activity
Also Known As:
GDC 0449; GDC-0449; GDC0449
Networked: 41 relevant articles (4 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. de Sauvage, Frederic J: 6 articles (01/2011 - 06/2009)
2. Yauch, Robert L: 5 articles (12/2012 - 09/2009)
3. Rudin, Charles M: 4 articles (04/2011 - 09/2009)
4. Hann, Christine L: 4 articles (04/2011 - 09/2009)
5. Low, Jennifer A: 4 articles (04/2011 - 09/2009)
6. Reddy, Josina C: 3 articles (12/2012 - 09/2009)
7. LoRusso, Patricia M: 3 articles (04/2011 - 09/2009)
8. Von Hoff, Daniel D: 3 articles (04/2011 - 09/2009)
9. Tibes, Raoul: 3 articles (04/2011 - 09/2009)
10. Gould, Stephen E: 3 articles (01/2011 - 09/2009)

Related Diseases

1. Neoplasms (Cancer)
2. Basal Cell Carcinoma (Rodent Ulcer)
3. Mesothelioma
4. Lung Neoplasms (Lung Cancer)
5. Adenocarcinoma

Related Drugs and Biologics

1. Itraconazole (Sporanox)
2. GANT 61
3. arsenic trioxide (Trisenox)
4. IPI-926
5. Topotecan (Hycamtin)
6. Triethylenephosphoramide (TEPA)
7. Tamoxifen
8. Messenger RNA (mRNA)
9. Mitoxantrone (Novantrone)
10. Micelles

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Homologous Transplantation (Allograft)
3. Drug Therapy (Chemotherapy)