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type 1 Autoimmune polyendocrinopathy syndrome

Also Known As:
Autoimmune polyendocrinopathy syndrome, type 1; APS 1; Autoimmune polyendocrine syndrome, type 1; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED); Hypoadrenocorticism with hypoparathyroidism and superficial moniliasis; PGA 1
Networked: 152 relevant articles (1 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Perheentupa, Jaakko: 7 articles (06/2015 - 06/2002)
2. Ulmanen, Ismo: 7 articles (10/2008 - 06/2002)
3. Kämpe, Olle: 6 articles (06/2015 - 06/2002)
4. Peltonen, Leena: 6 articles (10/2008 - 06/2002)
5. Peterson, Pärt: 5 articles (12/2011 - 07/2006)
6. Krohn, Kai: 4 articles (07/2015 - 07/2006)
7. Alimohammadi, Mohammad: 4 articles (06/2015 - 09/2006)
8. Anderson, Mark S: 4 articles (06/2015 - 05/2008)
9. Betterle, Corrado: 4 articles (05/2013 - 11/2008)
10. Eskelin, Petra: 4 articles (07/2006 - 06/2002)

Related Diseases

1. Autoimmune Diseases (Autoimmune Disease)
2. Autoimmune Polyendocrinopathies (Schmidt Syndrome)
3. Systemic Lupus Erythematosus (Libman-Sacks Disease)
4. Autoimmune Lymphoproliferative Syndrome
05/01/2008 - "Epidemiological data show that there are PIDs systematically associated with AID, such as immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), Omenn syndrome, autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), autoimmune lymphoproliferative syndrome (ALPS), and C1q deficiency, while strong associations are seen with a handful of other deficits. "
12/01/2005 - "Recent studies of autoimmune polyendocrinopathy syndrome type 1, autoimmune lymphoproliferative syndrome, immunodysregulation, polyendocrinopathy and enteropathy, X-linked, IL-2 receptor alpha-chain deficiency, and, in particular, their corresponding mouse models, have revealed the details of the molecular mechanisms of normal immune tolerance, and exposed how defects in these mechanisms result in human autoimmunity. "
05/01/2008 - "On the other hand and very interestingly, there are PIDs systematically associated with several autoimmune manifestations in which SLE has not been described, such as autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), immunodysregulation polyendocrinopathy enteropathy X-linked (IPEX), and autoimmune lymphoproliferative syndrome (ALPS), suggesting that mechanisms considered as critical players for induction and maintenance of tolerance to autoantigens, such as (1) AIRE-mediated thymic negative selection of lymphocytes, (2) Foxp3+ regulatory T cell-mediated peripheral tolerance, and (3) deletion of auto-reactive lymphocytes by Fas-mediated apoptosis, could not be relevant in SLE physiopathology. "
5. Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)

Related Drugs and Biologics

1. rituximab (Mabthera)
2. Interleukin-17 (Interleukin 27)
3. Prostaglandins A (PGA)
4. interleukin-22 (IL-22)
5. Neuroprotective Agents
6. Interleukin-2 Receptors (IL 2 Receptor)
7. Lithium
8. Heat-Shock Proteins (Heat-Shock Protein)
9. prostaglandin A1 (PGA1)
10. type 1 Autoimmune polyendocrinopathy syndrome

Related Therapies and Procedures

1. Catheters
2. Intraperitoneal Injections
3. Intravenous Infusions