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familial Danish Dementia

Cerebellar ataxia, cataract, deafness, and dementia or psychosis
Also Known As:
Dementia, familial Danish; Familial Danish dementia; Heredopathia ophthalmootoencephalica
Networked: 30 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Ghiso, Jorge: 9 articles (01/2016 - 03/2002)
2. Rostagno, Agueda: 8 articles (01/2016 - 03/2002)
3. Lashley, Tammaryn: 7 articles (05/2013 - 03/2002)
4. Vidal, Ruben: 6 articles (04/2015 - 03/2002)
5. Revesz, Tamas: 6 articles (05/2013 - 03/2002)
6. Frangione, Blas: 6 articles (07/2009 - 03/2002)
7. Plant, Gordon: 6 articles (07/2009 - 03/2002)
8. Holton, Janice L: 4 articles (07/2009 - 03/2002)
9. Holton, Janice: 3 articles (05/2013 - 12/2002)
10. Coomaraswamy, Janaky: 3 articles (05/2013 - 04/2010)

Related Diseases

1. Neurodegenerative Diseases (Neurodegenerative Disease)
2. Dementia (Dementias)
3. Alzheimer Disease (Alzheimer's Disease)
4. Amyloidosis
03/01/2002 - "Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta."
12/20/2002 - "Chromosome 13 dementias, familial British dementia (FBD) and familial Danish dementia (FDD), are associated with neurodegeneration and cerebrovascular amyloidosis, with striking neuropathological similarities to Alzheimer's disease (AD). "
10/01/2008 - "The reduction of brain pE-Abeta by inhibition of glutaminyl cyclase offers a new therapeutic option for the treatment of Alzheimer's disease and provides implications for other amyloidoses, such as familial Danish dementia."
01/01/2016 - "Familial Danish Dementia (FDD), an early-onset non-amyloid-β (Aβ) cerebral amyloidosis, is neuropathologically characterized by widespread cerebral amyloid angiopathy, parenchymal amyloid and preamyloid deposits, as well as neurofibrillary degeneration indistinguishable to that seen in Alzheimer's disease (AD). "
09/01/2003 - "Other amyloid proteins involved in familial CAAs include 1) the mutant cystatin C (ACys) in hereditary cerebral hemorrhage with amyloidosis of Icelandic type, 2) variant transthyretins (ATTR) in meningo-vascular amyloidoses, 3) mutated gelsolin (AGel) in familial amyloidosis of Finnish type, 4) disease-associated prion protein (PrP(Sc)) in a variant of the Gerstmann-Sträussler-Scheinker syndrome, and 5) ABri and ADan in CAAs observed in the recently described BRI2 gene-related dementias, familial British dementia and familial Danish dementia, respectively. "
5. Amyloid Plaque

Related Drugs and Biologics

1. familial British Dementia
2. Amyloid (Amyloid Fibrils)
3. Cystatin C
4. Gelsolin
5. Peptides
6. Amyloidogenic Proteins
7. Nonsense Codon (Nonsense Mutation)
8. Proteins (Proteins, Gene)
9. Prealbumin (Transthyretin)
10. Amyloid angiopathy

Related Therapies and Procedures

1. Ligation