HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

type v Syndactyly

Also Known As:

Syndactyly, type v; Syndactyly type 5; Syndactyly with metacarpal and metatarsal fusion

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Brachydactyly
2.	type 2 Syndactyly

Experts

1.	Amzel, L Mario: 1 article (02/2007)
2.	Ao, Yang: 1 article (02/2007)
3.	Jabs, Ethylin Wang: 1 article (02/2007)
4.	Leyva, J Alfonso: 1 article (02/2007)
5.	Liu, Guoyang: 1 article (02/2007)
6.	Liu, Qing: 1 article (02/2007)
7.	Lo, Wilson H Y: 1 article (02/2007)
8.	Shan, Xiangnian: 1 article (02/2007)
9.	Sun, Miao: 1 article (02/2007)
10.	Yang, Wei: 1 article (02/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to type v Syndactyly:

1.	Glutamine (L-Glutamine)FDA Link 02/01/2007 - "In the family with syndactyly type V, we identified a missense mutation in the HOXD13 homeodomain, c.950A-->G (p.Q317R), which leads to substitution of the highly conserved glutamine that is important for DNA-binding specificity and affinity. "
2.	DNA (Deoxyribonucleic Acid)IBA 02/01/2007 - "In the family with syndactyly type V, we identified a missense mutation in the HOXD13 homeodomain, c.950A-->G (p.Q317R), which leads to substitution of the highly conserved glutamine that is important for DNA-binding specificity and affinity. "
3.	polyalanineIBA 02/01/2007 - "Our data established the link between HOXD13 and two additional limb phenotypes--syndactyly type V and brachydactyly type A4--and demonstrated that a polyalanine contraction in HOXD13, most likely, led to other digital anomalies but not to synpolydactyly. "