Pallister W syndrome

A rare X-linked hereditary syndrome characterized by craniofacial abnormalities that include a prominent mandible, HYPERTELORISM, and distinct anterior cowlick, STRABISMUS; MUSCLE SPASTICITY; limited elbow motion, moderate to severe intellectual disability, and seizures. OMIM: 311450

Also Known As:

Networked: 13 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Supraventricular Tachycardia
2.	Tachycardia (Tachyarrhythmias)
3.	Ventricular Premature Complexes (Premature Ventricular Contraction)
4.	Ventricular Tachycardia
5.	Pneumothorax

Experts

1.	Krizova, Adriana: 1 article (04/2019)
2.	Nash, Michelle M: 1 article (04/2019)
3.	Prasad, G V Ramesh: 1 article (04/2019)
4.	Rapi, Lindita: 1 article (04/2019)
5.	West, Michael: 1 article (04/2019)
6.	Li, Yu-fen: 1 article (09/2009)
7.	Shi, Ji-jun: 1 article (09/2009)
8.	Ye, Ju-heng: 1 article (09/2009)
9.	Zeng, Shao-ying: 1 article (09/2009)
10.	Zhang, Zhi-wei: 1 article (09/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pallister W syndrome:

1.	LeptinIBA 12/01/1997 - "High leptin levels in Prader-Willi (P-W) syndrome may occur as a result of the existence of leptin resistance, because a hypothalamic disturbance may underlay this disorder. " 12/01/1997 - "In order to study whether there is a defective action of leptin on the hypothalamus in P-W syndrome, we have measured leptin and insulin twice during the daily profile of blood glucose, comparing the results with the recent reports. "
2.	Insulin (Novolin)FDA Link 12/01/1997 - "In order to study whether there is a defective action of leptin on the hypothalamus in P-W syndrome, we have measured leptin and insulin twice during the daily profile of blood glucose, comparing the results with the recent reports. "
3.	Blood Glucose (Blood Sugar)IBA 12/01/1997 - "In order to study whether there is a defective action of leptin on the hypothalamus in P-W syndrome, we have measured leptin and insulin twice during the daily profile of blood glucose, comparing the results with the recent reports. "
4.	Procainamide (Procan)FDA LinkGeneric 07/01/1975 - "To elucidate the mechanical consequences of ventricular pre-excitation in patients with the W,W syndrome, electrical and mechanical events in the ventricles during anomalous pathway conduction and normal atrioventricular conduction were examined mechanocardiographically in 11 cases of Group A and 19 cases of Group B, in whom anomalous pathway conduction was stopped by procaine amide, resulting in normalization of conduction. "
5.	CreatinineIBA 04/03/2019 - "The serum creatinine concentration may be unhelpful in assessing kidney function in K-W syndrome. "
6.	beta-Endorphin (Endorphin, beta)IBA 07/15/1983 - "The hypothesis that some of the symptoms of the P-L-W syndrome are due to excessive opioid activity is not supported by measurement of peripheral levels of ir-beta-endorphin."
7.	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 09/01/1982 - "Additional features supporting an immunologic pathogenesis of the BB/W syndrome include the protective action of antilymphocyte serum, neonatal bone marrow transfusions, and neonatal thymectomy. "
8.	Opioid Analgesics (Opioids)IBA 07/15/1983 - "The hypothesis that some of the symptoms of the P-L-W syndrome are due to excessive opioid activity is not supported by measurement of peripheral levels of ir-beta-endorphin."
9.	Amiodarone (Amiodarona)FDA LinkGeneric 02/01/1983 - "An esophageal lead was used to perform decremental atrial pacing and elective induction of atrial fibrillation (AF) in 5 patients with the Wolff-Parkinson-White (W-P-W) syndrome before and after amiodarone therapy. "
10.	landiololIBA 01/01/2005 - "We report here a case of cesarian section in a patient with R-W syndrome whose QT prolongation was successfully managed with landiolol, a selective beta1 receptor blocker. "

Therapies and Procedures

1.	Defibrillators (Defibrillator) 02/01/1994 - "Twenty-one were operated on account of W-P-W syndrome, 9 on account of ventricular tachycardia due to IHD and in 10 patients an automatic defibrillator was implanted. "
2.	Catheter Ablation 09/01/2009 - "Guided by Carto system, radiofrequency catheter ablation (RFCA) was performed on 8 pediatric patients with tachycardia whose mean age was (6.2 + or - 1.7) years, mean weight was (18.0 + or - 2.0) kg. Guided by Ensite system, RFCA was performed on 10 pediatric patients with arrhythmia, 8 of them were ablated guided by Ensite Array system: 6 cases with premature ventricular contractions (PVCs), 2 cases with right atrial tachycardia, their mean age was (11.3 + or - 1.2) years, and mean weight (40.0 + or - 5.0) kg. The other two cases with W-P-W syndrome were ablated guided by Ensite Navx system. "
3.	Thymectomy 09/01/1982 - "Additional features supporting an immunologic pathogenesis of the BB/W syndrome include the protective action of antilymphocyte serum, neonatal bone marrow transfusions, and neonatal thymectomy. "
4.	Therapeutics 02/01/1983 - "An esophageal lead was used to perform decremental atrial pacing and elective induction of atrial fibrillation (AF) in 5 patients with the Wolff-Parkinson-White (W-P-W) syndrome before and after amiodarone therapy. "
5.	Postoperative Care 12/01/1984 - "[Pre- and postoperative care of patients undergoing operations for W-P-W syndrome]."