Bamforth syndrome

Also Known As:

Bamforth-Lazarus syndrome; Hypothyroidism cleft palate; Hypothyroidism, Thyroidal, With Spiky Hair And Cleft Palate; Hypothyroidism, athyroidal, with spiky hair and cleft palate

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
Musculoskeletal Diseases: 719
- Musculoskeletal Abnormalities: 43
  - Craniofacial Abnormalities: 203
    - Maxillofacial Abnormalities: 10
      - Jaw Abnormalities: 10
        Cleft Palate: 2757
        Bamforth syndrome: 4
- Jaw Diseases: 15
  - Jaw Abnormalities: 10
    - Cleft Palate: 2757
      - Bamforth syndrome: 4
Stomatognathic Diseases: 705
Skin and Connective Tissue Diseases
- Skin Diseases: 13127
  - Hair Diseases: 36
    - Bamforth syndrome: 4
Endocrine System Diseases: 968
- Thyroid Diseases: 6126
  - Hypothyroidism: 16964
    - Bamforth syndrome: 4

Related Diseases

1.	Paralysis (Palsy)
2.	Hypothyroidism
3.	Fetal Diseases (Embryopathy)
4.	Cleft Palate (Palate, Cleft)
5.	Choanal Atresia

Experts

1.	Iida, Atsumi: 1 article (12/2009)
2.	Nakada, Chisako: 1 article (12/2009)
3.	Tabata, Yoko: 1 article (12/2009)
4.	Watanabe, Sumiko: 1 article (12/2009)
5.	Baris, Ibrahim: 1 article (08/2006)
6.	Solak, Mine: 1 article (08/2006)
7.	Toker, Kamil: 1 article (08/2006)
8.	Yildiz, Tulay Sahin: 1 article (08/2006)
9.	Antonini, Dario: 1 article (11/2004)
10.	Brancaccio, Anna: 1 article (11/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Bamforth syndrome:

1.	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 11/01/2004 - "The forkhead transcription factor FOXE1 is mutated in patients with Bamforth-Lazarus syndrome that exhibit hair follicle defects, suggesting a possible role for Foxe1 in hair follicle morphogenesis. " 12/15/2009 - "Forkhead transcription factor (Fox) e1 is a causative gene for Bamforth-Lazarus syndrome, which is characterized by hypothyroidism and cleft palate. "
2.	Methimazole (Thiamazole)FDA LinkGeneric 04/01/2002 - "Two sibs from an inbred Arab family are described with an autosomal syndrome of choanal atresia, hypothelia/athelia and thyroid gland anomalies overlapping Bamforth syndrome, ANOTHER syndrome and methimazole embryopathy. " 04/01/2002 - "An autosomal recessive syndrome of choanal atresia, hypothelia/athelia and thyroid gland anomalies overlapping bamforth syndrome, ANOTHER syndrome and methimazole embryopathy."
3.	Mivacurium (Mivacron)FDA Link 08/01/2006 - "Unexpected prolonged paralysis after mivacurium in a patient with Bamforth syndrome."