|1.||Anum, Tooba: 1 article (01/2013)|
|2.||German, Sidra: 1 article (01/2013)|
|3.||Saleem, Shafaq: 1 article (01/2013)|
|4.||Raees, Aisha: 1 article (01/2013)|
|5.||Aslam, Hafiz Muhammad: 1 article (01/2013)|
|6.||Alvi, Arsalan Ahmad: 1 article (01/2013)|
|7.||Haseeb, Abdul: 1 article (01/2013)|
|8.||Laganà, Francesco: 1 article (01/2005)|
|9.||Gobbi, Roberta: 1 article (01/2005)|
|10.||Corradi, Domenico: 1 article (01/2005)|
09/01/1996 - "For 2/3 MIN+ OC cases with family cancer history consistent with the Lynch cancer family syndrome, we found additional bands in the microsatellite patterns in tumor versus normal tissue (HNPCC-type of MIN), but no germline mutations in two DNA mismatch repair genes, hMSH2 and hMLH1. "
08/01/1994 - "In many instances there is a strong family history of cancer and the autosomal dominant mode of inheritance, tumour spectrum, and high incidence of synchronous and metachronous tumours show parallels with the cancer family syndrome or Lynch II syndrome. "
01/01/1993 - "The tumor suppressor gene p53 is involved in predisposition to a variety of human cancers, including those from Li-Fraumeni cancer family syndrome patients. "
01/01/1992 - "The finding of cancer aggregation in the family corresponded to the criteria for the cancer family syndrome."
09/01/1991 - "The distribution of different malignant tumors was studied in 40 cancer family syndrome (CFS) families with 315 affected family members and a total of 472 separate tumors or malignant diseases. "
|2.||Colorectal Neoplasms (Colorectal Cancer)
04/01/1987 - "[Clinicopathological study of colorectal cancer in young adults including a case of cancer family syndrome]."
11/01/1992 - "Eighty-two pedigrees were compatible with a diagnosis of a multiple-site cancer family syndrome and the relative risks were 6.1, 2.8, 3.7, and 2.7 for ovarian, breast, stomach, and colorectal cancer, respectively. "
08/01/1989 - "Hereditary nonpolyposis colorectal carcinoma: cancer family syndrome."
01/01/1988 - "One example is the cancer family syndrome (CFS), where colorectal carcinoma is transmitted in an autosomal dominant mode. "
05/01/1987 - "Screening for colorectal carcinoma (CRC) was organized for 236 asymptomatic family members in 22 Finnish cancer family syndrome (CFS) kindreds, and 58% (137) of the subjects accepted the invitation. "
|3.||Colonic Neoplasms (Colon Cancer)
10/01/1982 - "Group 1 consisted of 5 cancer family syndrome individuals previously diagnosed with colon cancer. "
10/01/1981 - "[Key words: Cancer, colonic, familial; Cancer Family Syndrome."
10/01/1981 - "A report of the history and management of colonic cancer in two brothers with Cancer Family Syndrome is presented. "
03/15/1980 - "Patients with sporadic or hereditary colon cancer (cancer family syndrome) demonstrate in vitro defects of cellular immunity characterized by decreased lymphocyte responsiveness in mixed leukocyte culture, which can frequently be attributed to the influence of suppressor macrophages. "
03/01/1979 - "Specific attention has been given to the problems of screening patients at risk for the development of proximal colonic cancer, an important feature of the cancer-family syndrome. "
07/01/1990 - "Cancer family syndrome: cytogenetic investigations, in vitro tetraploidy, and biomarker studies in a large family."
07/01/1990 - "Fifty-five members of a family with the cancer family syndrome (CFS) were investigated for the following potential biomarkers for cancer proneness: (1) cytogenetics of peripheral blood lymphocytes and skin fibroblasts; (2) in vitro tetraploidy of dermal fibroblast monolayer cultures; (3) quantitative serum immunoglobulin determinations; (4) study of genetic linkage with respect to eight blood group markers including Kidd. "
08/15/1985 - "Nine families with the cancer family syndrome (CFS), or Lynch syndrome II, and two with hereditary site-specific colonic cancer (HSSCC), or Lynch syndrome I, were investigated for the following potential biomarkers of genotype status: in vitro tetraploidy of dermal fibroblast monolayer cultures; tritiated thymidine uptake (3HdThd) labeling of colonic mucosa; cytogenetics of peripheral blood mononuclear leukocytes; quantitative serum immunoglobulin determinations; methionine dependence in dermal fibroblasts in tissue culture; segregation analysis; and the study of gene linkage with respect to 25 landmark serum and blood group markers. "
08/01/1989 - "High frequency of CRC and some other adenocarcinomas with early age of onset, with common multiplicity and with dominant mode of genetic transmission are characteristic for this inherited disorder originally called the cancer family syndrome (CFS). "
01/01/1989 - "Individuals from kindred with cancer family syndrome (CFS) have an increased genetic risk for the development of adenocarcinoma of the colon as well as of several other organs. "
09/01/1986 - "Individuals from kindreds with the cancer family syndrome (CFS) have an increased hereditary risk for the development of adenocarcinoma of the colon in childhood and early adulthood. "
11/01/1992 - "Our preliminary data not only show familial and probably heritable tendencies for endometrial adenocarcinoma, but further suggest that there are at least two distinct forms: (1) the previously described Lynch syndrome II (cancer family syndrome), and (2) a heretofore unemphasized entity characterized by a tendency to endometrial adenocarcinoma alone."
11/01/1992 - "In four other families, multiple first- and second-degree relatives of probands had adenocarcinoma of the uterus, colon, or ovary, presumably representing a cancer family syndrome (Lynch syndrome II). "
|1.||Biological Markers (Surrogate Marker)
|7.||DNA (Deoxyribonucleic Acid)