multiple Basal cell carcinoma

A genetically heterogeneous trait that confers susceptibility to cutaneous basal cell carcinoma in people of European descent; several susceptibility loci have been mapped. OMIM: 605462.

Also Known As:

Networked: 18 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Xeroderma Pigmentosum (Kaposi's Disease)
2.	Skin Neoplasms (Skin Cancer)
3.	Oral Leukoplakia
4.	Odontogenic Cysts (Keratocyst)
5.	Basal Cell Nevus Syndrome (Gorlin Syndrome)

Experts

1.	Baas, Paul: 2 articles (11/2006 - 02/2003)
2.	Aarts, Maureen J B: 1 article (01/2021)
3.	Alers, Robert-Jan: 1 article (01/2021)
4.	Bekkenk, Marcel W: 1 article (01/2021)
5.	Devriese, Lot A: 1 article (01/2021)
6.	Kapiteijn, Ellen: 1 article (01/2021)
7.	Mosterd, Klara: 1 article (01/2021)
8.	Nelemans, Patty: 1 article (01/2021)
9.	Reinders, Marie G H C: 1 article (01/2021)
10.	Reyners, An K L: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to multiple Basal cell carcinoma:

1.	1-phenyl-3,3-dimethyltriazene (PDT)IBA 02/01/2013 - "To report our experience of methylaminolevulinate photodynamic therapy (MAL-PDT) in the treatment of multiple basal cell carcinoma (BCC) in adults and children with Gorlin syndrome (GS). " 02/01/2003 - "In one patient with multiple basal cell carcinoma, the effect of the combination of 5-fluorouracil administration followed by PDT resulted in significantly stronger effects than expected, leading to severe oedema, redness and ulceration. " 11/01/2006 - "Meso-tetra-hydroxyphenyl-chlorin (mTHPC)-mediated photodynamic therapy (PDT) has shown to be effective in the treatment of patients with multiple basal cell carcinoma (BCC). "
2.	temoporfinIBA 11/01/2006 - "Meso-tetra-hydroxyphenyl-chlorin (mTHPC)-mediated photodynamic therapy (PDT) has shown to be effective in the treatment of patients with multiple basal cell carcinoma (BCC). "
3.	RetinoidsIBA 10/01/1994 - "Though the mechanism of action of retinoids is not yet fully understood at the molecular level, chemoprevention studies have demonstrated the ability of retinoids to prevent the development of skin cancer, particularly in patients with xeroderma pigmentosum, multiple basal cell carcinoma and oral leukoplakia. "
4.	HhAntag691IBA 01/01/2023 - "Retrospective Real-Life Data, Efficacy and Safety of Vismodegib Treatment in Patients with Advanced and Multiple Basal Cell Carcinoma: 3-Year Experience from a Spanish Center." 01/01/2021 - "Eight years of experience with vismodegib for advanced and multiple basal cell carcinoma patients in the Netherlands: a retrospective cohort study."
5.	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 06/30/2023 - "We present the compelling whole-body bone scan and 18F-FDG PET/CT findings in a 32-year-old man with odontogenic keratocyst, early-onset basal cell carcinoma, multiple ectopic calcifications in extremities, calcified falx cerebri, spinal scoliosis, macrocephaly, and ocular hypertelorism."
6.	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 04/01/1997 - "Truncal tumor site is associated with high risk of multiple basal cell carcinoma and is influenced by glutathione S-transferase, GSTT1, and cytochrome P450, CYP1A1 genotypes, and their interaction."
7.	Parathyroid Hormone (Parathormone)IBA 03/01/1979 - "A patient with multiple basal cell carcinoma syndrome, a symptom complex characteristized by nevoid basal cell carcinomas of the skin, jaw cysts, skeletal abnormalities, and hyporesponsiveness to parathormone is presented. "
8.	Ointments (Pastes)IBA 01/01/2002 - "The effectiveness of glycifone ointment treatment for primary multiple basal cell carcinoma of the skin was evaluated in 28 patients. "
9.	Fluorouracil (Carac)FDA LinkGeneric 02/01/2003 - "In one patient with multiple basal cell carcinoma, the effect of the combination of 5-fluorouracil administration followed by PDT resulted in significantly stronger effects than expected, leading to severe oedema, redness and ulceration. "
10.	Estrogens (Estrogen)FDA Link 04/01/1956 - "[Experimental production of cutaneous neoplastic proliferation by scarification and estrogen application in a case of multiple basal cell carcinoma of the trunk]."

Therapies and Procedures

1.	Photochemotherapy (Photodynamic Therapy) 10/01/2023 - "Neoadjuvant photodynamic therapy as a therapeutic alternative in multiple basal cell carcinoma induced by radiotherapy." 02/01/2013 - "To report our experience of methylaminolevulinate photodynamic therapy (MAL-PDT) in the treatment of multiple basal cell carcinoma (BCC) in adults and children with Gorlin syndrome (GS). " 11/01/2006 - "Meso-tetra-hydroxyphenyl-chlorin (mTHPC)-mediated photodynamic therapy (PDT) has shown to be effective in the treatment of patients with multiple basal cell carcinoma (BCC). "
2.	Chemoprevention 10/01/1994 - "Though the mechanism of action of retinoids is not yet fully understood at the molecular level, chemoprevention studies have demonstrated the ability of retinoids to prevent the development of skin cancer, particularly in patients with xeroderma pigmentosum, multiple basal cell carcinoma and oral leukoplakia. "
3.	Radiotherapy 10/01/2023 - "Neoadjuvant photodynamic therapy as a therapeutic alternative in multiple basal cell carcinoma induced by radiotherapy." 07/01/2000 - "To our knowledge this is the first case of multiple basal cell carcinoma in addition to a malignant melanoma following radiotherapy for benign disease."
4.	X-Ray Therapy 11/01/1979 - "Multiple basal cell carcinoma 58 years after X-ray therapy."
5.	Therapeutics 01/01/2002 - "[Experience with glyciphonic ointment therapy for primary multiple basal cell carcinoma of the skin]."