Rhabdomyosarcoma of the orbit

An orbital neoplasm that occurs primarily in children under 15 years of age. Most are EMBRYONAL NEOPLASMS that arise from primitive mesenchymal cells which differentiate into striated muscle cells. Alveolar orbital rhabdomyosarcomas are less common and typically occur in adolescents and young adults.

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Rhabdomyosarcoma
2.	Alveolar Rhabdomyosarcoma
3.	Melanoma (Melanoma, Malignant)
4.	Down Syndrome (Down's Syndrome)

Experts

1.	Desjardins, Laurence: 1 article (08/2002)
2.	Jouffroy, Thomas: 1 article (08/2002)
3.	Levy, Christine: 1 article (08/2002)
4.	Lumbroso, Livia: 1 article (08/2002)
5.	Rodriguez, José: 1 article (08/2002)
6.	Sigal-Zafrani, Brigitte: 1 article (08/2002)
7.	Anderson, J R: 1 article (06/2000)
8.	Crist, W M: 1 article (06/2000)
9.	Glicksman, A S: 1 article (06/2000)
10.	Heyn, R: 1 article (06/2000)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Rhabdomyosarcoma of the orbit:

1.	VimentinIBA 06/01/1990 - "An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). "
2.	S100 Proteins (S 100 Protein)IBA 06/01/1990 - "An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). "
3.	MyoglobinIBA 06/01/1990 - "An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). "
4.	Keratins (Keratin)IBA 06/01/1990 - "An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). "
5.	DesminIBA 06/01/1990 - "An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). "
6.	AntibodiesIBA 06/01/1990 - "An immunohistochemical analysis using a series of mono- and polyclonal antibodies against myoglobin, desmin, vimentin, actin, NSE, S-100 protein and keratin was done on alveolar rhabdomyosarcoma (3 cases), embryonal (3) and pleomorphic rhabdomyosarcoma of the orbit (1). "
7.	Alkylating AgentsIBA 11/15/1991 - "The second child had Down syndrome and received alkylating agents and radiation therapy for treatment of metastatic rhabdomyosarcoma of the orbit. "

Therapies and Procedures

1.	Therapeutics 06/01/2000 - "We reviewed the late complications of therapy in 94 patients with localized, primary rhabdomyosarcoma of the orbit treated on the Intergroup Rhabdomyosarcoma Study (IRS)-III protocol (1984-1991). " 06/01/2000 - "Late effects of therapy in 94 patients with localized rhabdomyosarcoma of the orbit: Report from the Intergroup Rhabdomyosarcoma Study (IRS)-III, 1984-1991."
2.	Radiotherapy 11/01/1968 - "Radiation therapy for rhabdomyosarcoma of the orbit." 07/01/1991 - "The role of chemotherapy, surgery, and radiotherapy in rhabdomyosarcoma of the orbit." 11/15/1991 - "The second child had Down syndrome and received alkylating agents and radiation therapy for treatment of metastatic rhabdomyosarcoma of the orbit. "
3.	Drug Therapy (Chemotherapy) 01/01/1982 - "In patients with rhabdomyosarcoma of the orbit it is justified to avoid the mutilating exenteration by primary chemotherapy followed by irradiation of the reduced manner. " 07/01/1991 - "The role of chemotherapy, surgery, and radiotherapy in rhabdomyosarcoma of the orbit."
4.	Aftercare (After-Treatment) 08/01/2002 - "Late malignant melanoma after treatment of rhabdomyosarcoma of the orbit during childhood."