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Jensen syndrome
Also Known As:
Nerve deafness optic nerve atrophy, and dementia; Opticoacoustic Nerve Atrophy With Dementia; Opticoacustic nerve atrophy with dementia; Syndrome of opticoacoustic nerve atrophy with dementia
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Disease Context: Research Results
Nervous System Diseases: 14178
Neurologic Manifestations: 7102
Sensation Disorders: 117
Hearing Disorders: 325
Hearing Loss: 12265
Sensorineural Hearing Loss: 3974
Central Hearing Loss: 6
Jensen syndrome: 1
Central Nervous System Diseases: 4213
Brain Diseases: 15694
Dementia: 38184
Jensen syndrome: 1
Central Auditory Diseases: 12
Central Hearing Loss: 6
Jensen syndrome: 1
Cranial Nerve Diseases: 554
Optic Nerve Diseases: 2663
Optic Atrophy: 819
Jensen syndrome: 1
Mental Disorders: 24177
Neurocognitive Disorders: 1448
Dementia: 38184
Jensen syndrome: 1
Otorhinolaryngologic Diseases: 203
Ear Diseases: 261
Hearing Disorders: 325
Hearing Loss: 12265
Sensorineural Hearing Loss: 3974
Central Hearing Loss: 6
Jensen syndrome: 1
Retrocochlear Diseases: 5
Central Auditory Diseases: 12
Central Hearing Loss: 6
Jensen syndrome: 1
Signs and Symptoms Pathological Conditions
Signs and Symptoms
Neurologic Manifestations: 7102
Sensation Disorders: 117
Hearing Disorders: 325
Hearing Loss: 12265
Sensorineural Hearing Loss: 3974
Central Hearing Loss: 6
Jensen syndrome: 1
Eye Diseases: 3522
Optic Nerve Diseases: 2663
Optic Atrophy: 819
Jensen syndrome: 1
Related Diseases
1.
Intellectual Disability (Idiocy)
Experts
1.
Hatch, Hayden A M
: 1 article (09/2021)
2.
Secombe, Julie
: 1 article (09/2021)
Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Jensen syndrome:
1.
Histone Demethylases
IBA
12/01/2022 - "
Molecular and cellular events linking variants in the histone demethylase KDM5C to the intellectual disability disorder Claes-Jensen syndrome.
"
12/01/2022 - "
One gene found to be genetically altered in the X-linked intellectual disability disorder Claes-Jensen syndrome is KDM5C, which encodes a histone demethylase that regulates transcription by altering chromatin.
"
2.
Chromatin
IBA
12/01/2022 - "
One gene found to be genetically altered in the X-linked intellectual disability disorder Claes-Jensen syndrome is KDM5C, which encodes a histone demethylase that regulates transcription by altering chromatin.
"
Therapies and Procedures
1.
Therapeutics
12/01/2022 - "
Continued research into the molecular and cellular activities regulated by KDM5C is expected to provide critical etiological insights into Claes-Jensen syndrome and highlight potential targets for developing therapies to improve the quality of life of those affected.
"