Pili annulati

A condition where scalp hairs show alternating light and dark bands. It usually presents in infancy or early childhood and the hair does not have increased fragility. OMIM: 180600

Also Known As:

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Monilethrix

Experts

1.	Dawber, R P R: 3 articles (07/2005 - 04/2004)
2.	Giehl, K A: 3 articles (07/2005 - 04/2004)
3.	Miteva, Mariya: 2 articles (09/2016 - 09/2016)
4.	Singh, Gaurav: 2 articles (09/2016 - 09/2016)
5.	Dean, D: 2 articles (07/2005 - 04/2004)
6.	Wojnarowska, F: 2 articles (07/2005 - 04/2004)
7.	de Berker, D A R: 2 articles (07/2005 - 11/2004)
8.	Ferguson, D J P: 2 articles (11/2004 - 04/2004)
9.	Leigh, I: 1 article (07/2005)
10.	Foehles, J: 1 article (11/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pili annulati:

1.	Cystine (L-Cystine)IBA 09/01/1981 - "In this study we have shown that in pili annulati all the normal layers within each cuticle cell are present, and show a normal distribution of cystine. " 11/01/2004 - "Amino acid analysis of the hair of three patients with pili annulati showed elevated lysine and decreased cystine content compared to 12 normal controls, consistent with the reduced threshold for weathering. "
2.	Minoxidil (Rogaine)FDA LinkGeneric 09/01/2016 - "Others, such as trichorrhexis nodosa, monilethrix, pili annulati, and pili bifurcati, improve with minoxidil. " 09/01/2016 - "Others, such as trichorrhexis nodosa, monilethrix, pili annulati, and pili bifurcati improve with minoxidil. "
3.	Keratins (Keratin)IBA 07/01/2005 - "This is the first investigation of the proposed cytokeratin defect in pili annulati hair follicles. " 07/01/2005 - "Cytokeratin expression in pili annulati hair follicles." 01/01/1988 - "Pili annulati may be a disorder of protein metabolism involving a partial dysfunction of cytoplasmic ribosomes, resulting in a lack of cortical keratin formation."
4.	Integrin alpha6beta4IBA 04/01/2004 - "The expression of the hemidesmosome-associated alpha(6)beta(4) integrin was linear in both pili annulati and control hair follicles. " 04/01/2004 - "Longitudinal sections of scalp tissues from four individuals with pili annulati and six normal controls were studied by immunohistochemistry with a panel of monoclonal antibodies to the following BMZ components: alpha(6)beta(4) integrin, laminin 5, LH39 antigen, laminin 1, collagen IV and collagen VII. Using TEM, pili annulati scalp specimens exhibited a reduplicated lamina densa in the region of the root bulb in comparison with the single thin electron-dense band in controls. "
5.	ZincIBA 09/01/1990 - "The plasmatic measurement of copper, zinc and of the most important hormone, such as the dosage of plasmatic, urinary and hair aminoacids, allowed the Authors to exclude any influence of metabolic systemic alterations on the pathogenesis of pili annulati. "
6.	Proteins (Proteins, Gene)FDA Link 01/01/1988 - "Pili annulati may be a disorder of protein metabolism involving a partial dysfunction of cytoplasmic ribosomes, resulting in a lack of cortical keratin formation."
7.	Lysine (L-Lysine)FDA Link 11/01/2004 - "Amino acid analysis of the hair of three patients with pili annulati showed elevated lysine and decreased cystine content compared to 12 normal controls, consistent with the reduced threshold for weathering. "
8.	Hormones (Hormone)IBA 09/01/1990 - "The plasmatic measurement of copper, zinc and of the most important hormone, such as the dosage of plasmatic, urinary and hair aminoacids, allowed the Authors to exclude any influence of metabolic systemic alterations on the pathogenesis of pili annulati. "
9.	CopperIBA 09/01/1990 - "The plasmatic measurement of copper, zinc and of the most important hormone, such as the dosage of plasmatic, urinary and hair aminoacids, allowed the Authors to exclude any influence of metabolic systemic alterations on the pathogenesis of pili annulati. "
10.	CollagenIBA 04/01/2004 - "Longitudinal sections of scalp tissues from four individuals with pili annulati and six normal controls were studied by immunohistochemistry with a panel of monoclonal antibodies to the following BMZ components: alpha(6)beta(4) integrin, laminin 5, LH39 antigen, laminin 1, collagen IV and collagen VII. Using TEM, pili annulati scalp specimens exhibited a reduplicated lamina densa in the region of the root bulb in comparison with the single thin electron-dense band in controls. "